42 Results for "

polyols

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "polyols" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-107799
CAS No.: 8001-79-4
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .
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2
2 Cited Publications
Cat. No.: HY-50289
CAS No.: 68367-52-2
Target:  

Aldose Reductase

Research Areas:  

Metabolic Disease

Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway.
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1
1 Cited Publications
Cat. No.: HY-B0400B
CAS No.: 50-70-4
Synonyms: Sorbito, for cell culture; D-Glucitol, for cell culture
D-Sorbitol (D-Glucitol), for cell culture is a six-carbon sugar alcohol that can be used as a sugar substitute. D-Sorbitol, for cell culture serves as an osmotic regulator, cryoprotectant and carbon source in various plant and microbial cell culture media .
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1
1 Cited Publications
Cat. No.: HY-B1202
CAS No.: 51411-04-2
Synonyms: AY-22284
Target:  

Aldose Reductase

Research Areas:  

Metabolic Disease

Alrestatin (AY-22284) is an aldose reductase inhibitor. Alrestatin reduces fructose levels in the uterine fluid of mice. Alrestatin interferes with sperm capacitation and impairs fertilization function in mice. Alrestatin decreases basal and tyramine-induced norepinephrine release in rat pancreatic specimens in vitro. Alrestatin enhances glucose- and arginine-stimulated insulin secretion in vivo. Alrestatin can be used in studies related to diabetes and reproductive diseases .
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Cat. No.: HY-N7426
CAS No.: 4084-27-9
Synonyms: 3-Deoxy-D-glucosone
3-Deoxyglucosone (3-Deoxy-D-glucosone) is a reactive intermediate of the Maillard reaction and the polyol pathway. 3-Deoxyglucosone rapidly reacts with protein amino groups to form advanced glycation end products (AGEs), such as imidazolone, it is the most specific AGE for 3-DG. 3-Deoxyglucosone synergizes with low glucose to potentiate GLP-1 secretion and is considered as a biomarker for diabetes .
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Cat. No.: HY-N0538
CAS No.: 87-99-0
Synonyms: Xylite
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .
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Cat. No.: HY-B2122
CAS No.: 585-88-6
Maltitol is an orally active polyol and sugar alcohol sweetener produced by the hydrogenation of maltose. Maltitol can replace sucrose and has characteristics of having a minor impact on blood sugar and potential prebiotic effects .
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Cat. No.: HY-N7393
CAS No.: 64519-82-0
Synonyms: Palatinitol
Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes .
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Cat. No.: HY-N0538R
CAS No.: 87-99-0
Synonyms: Xylite (Standard)
Xylitol (Standard) is the analytical standard of Xylitol. This product is intended for research and analytical applications. Xylitol can be classified as polyols and sugar alcohols.
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Cat. No.: HY-E70398
CAS No.: 9028-21-1
Synonyms: L-Iditol dehydrogenase; Polyol dehydrogenase; SDH
Research Areas:  

Metabolic Disease

Sorbitol dehydrogenase (L-Iditol dehydrogenase) is an oxidoreductasea and catalyses the conversion of sorbitol to fructose with NAD + as the coenzyme. Sorbitol dehydrogenase catalyses pH-dependent redox reactions between NAD +/NADH and sorbitol/fructose. Sorbitol dehydrogenase is implicated in diabetic complications and is a biomarker of drug-induced liver injury. Sorbitol dehydrogenase can be used for the research of diabetes and liver injury .
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Cat. No.: HY-P2725
CAS No.: 9028-14-2
Research Areas:  

Metabolic Disease

Glycerol dehydrogenase is a polyol dehydrogenase that catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone. Glycerol dehydrogenase can be used for glycerol metabolism in diverse microorganisms .
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Cat. No.: HY-139312
CAS No.: 643-01-6
L-Mannitol is a synthetic L-configured acyclic sugar alcohol. L-Mannitol scavenges free radicals, reduces injection-related inflammation and swelling, and inhibits hyaluronic acid degradation. L-Mannitol can be oxidized as a substrate to L-fructose. L-Mannitol serves as a pharmaceutical excipient and can be used in relevant research in the food and pharmaceutical fields .
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Cat. No.: HY-N10695
CAS No.: 1000784-44-0
Celangulatin C is an insecticidal sesquiterpene polyol ester, that can be isolated from the root bark of Pseudolarix kaempferi. Celangulatin C shows LD50 against Mythimna separata of 280.4 μg/mL .
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Cat. No.: HY-N10639
CAS No.: 128443-60-7
Target:  

Others

Research Areas:  

Others

(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran is a sesquiterpene polyol ester. (1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran can be used for the research of various biochemical .
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Cat. No.: HY-W012663
CAS No.: 106-69-4
Research Areas:  

Others

1,2,6-Hexanetriol, a polyol, is an intermediate for wetting agents, solvents, and pharmaceuticals with excellent moisturizing property. 1,2,6-Hexanetriol is a humectant and plasticizer for hydrophilic films. 1,2,6-Hexanetriol has no significant toxicity in rats, rabbits, and dogs via oral (16 mL/kg), intraperitoneal (10 g/kg) and intravenous (5.6 mL/kg) routes. 1,2,6-Hexanetriol can be used for the cosmetics and resin industries .
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Cat. No.: HY-N10697
CAS No.: 1000784-46-2
Synonyms: Celangulatin E
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD50 against Mythimna separata of 1656.4 μg/mL .
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Cat. No.: HY-B2122R
CAS No.: 585-88-6
Maltitol (Standard) is the analytical standard of Maltitol (HY-B2122). This product is intended for research and analytical applications. Maltitol is an orally active polyol and sugar alcohol sweetener produced by the hydrogenation of maltose. Maltitol can replace sucrose and has characteristics of having a minor impact on blood sugar and potential prebiotic effects .
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Cat. No.: HY-131542
CAS No.: 100750-39-8
Research Areas:  

Metabolic Disease

APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research .
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Cat. No.: HY-N12657
Target:  

Others

Retinestatin, a new polyol polyketide, can protect SH-SY5Y dopaminergic cells from MPP + (HY-W008719)-induced cytotoxicity. Retinestatin shows neuroprotective effects in an in vitro model of Parkinson’s disease .
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Cat. No.: HY-N7871
CAS No.: 1631992-80-7
Angulatin K is a natural sesquiterpene polyol ester found in the root bark of Celastrus angulatus .
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