100750-39-8
100750-39-8
Chemical Structure
APPA
- CAS No.: 100750-39-8
- Formula:C14H13NO3
- Molecular Weight:243.26
IUPAC Name: 1-acetyl-5-phenyl-1H-pyrrol-3-yl acetate
InChIKey: WKSITCBIIIHVSF-UHFFFAOYSA-N
SMILES: CC(N1C(C2=CC=CC=C2)=CC(OC(C)=O)=C1)=O
Biological Activity: APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research[1].
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APPA | APPA is an aldose reductase inhibitor. APPA can effectively prevent apoptosis and the symptoms of Streptozotocin (HY-13753)-induced diabetes by inhibiting the polyol pathway in rats. APPA has the potential for diabetic nephropathy (DN) research. | |||||||||||||||||||||
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