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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
prmt5-in-27
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "prmt5-in-27" in MCE Product Catalog:
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PRMT5-IN-20 (P31 Claim 1) is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), and it can be used in cancer research .
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PRMT5-IN-2 is a rotein arginine methyltransferase 5 (PRMT5) inhibitor extracted from patent WO2018130840A1, compound 3 .
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PRMT5-IN-29 is a potent and orally active PRMT5 Inhibitor with an IC50 of 1.5 μΜ. PRMT5-IN-29 has the potential for advanced cancers research .
Cat. No.: HY-144188
CAS No.: 2755304-03-9
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PRMT5-IN-17 (Compound 6) is a PRMT5 inhibitor with anti-tumor activity. PRMT5 is a type of protein arginine methyltransferase, and is a new anti-tumor target related to epigenetic modification .
Cat. No.: HY-150081
CAS No.: 2922673-38-7
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PRMT5-IN-21 (compound 1) is a potent cyclonucleoside PRMT5 inhibitor .
Cat. No.: HY-153421
CAS No.: 2242753-66-6
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PRMT5-IN-28 (compound 36) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) enzyme. Protein arginine methylation is a common post-translational modification involved in gene transcription, mRNA splicing, DNA repair, protein cellular localization, cell fate determination and signal transduction, etc. Abnormal PRMT5 can promote cancer cell proliferation, resist apoptosis, enhance invasion and metastasis, and affect immune escape .
Cat. No.: HY-163586
CAS No.: 3034033-98-9
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PRMT5-IN-37 (compound 29) is an orally active PRMT5 inhibitor and can be used for study of cancer .
Cat. No.: HY-168842
CAS No.: 3065081-87-7
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PRMT5-IN-47 (compound 20) is a potent, selectively and orally active, MTA cooperative PRMT5 inhibitor with an IC50 value of 15 nM. PRMT5-IN-47 shows antiproliferative activity. PRMT5-IN-47 shows anticancer activity .
Cat. No.: HY-P3822
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Cat. No.: HY-111213A
CAS No.: 1047976-55-5
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PRMT5-IN-20 (P31 Claim 1) hydrochloride is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), and it can be used in cancer research .
Cat. No.: HY-184434
CAS No.: 3064280-41-4
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PRMT5-IN-57 is an orally active andselective MTA-cooperative PRMT5 inhibitor, with an IC50 of 8.39 nM against PRMT5/MTA complex. PRMT5-IN-57 exhibits potent and selective antiproliferative activity against MTAP-null cancer cells. PRMT5-IN-57 demonstrates significant in vivo antitumor efficacy in an HCT116 MTAP-/- CDX model. PRMT5-IN-57 can be used for the research of MTAP-deleted cancers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
