PRMT5-IN-28
PRMT5-IN-28 (compound 36) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) enzyme. Protein arginine methylation is a common post-translational modification involved in gene transcription, mRNA splicing, DNA repair, protein cellular localization, cell fate determination and signal transduction, etc. Abnormal PRMT5 can promote cancer cell proliferation, resist apoptosis, enhance invasion and metastasis, and affect immune escape.
For research use only. We do not sell to patients.
- CAS No.: 2242753-66-6
- Formula: C18H19ClN4O5
- Molecular Weight:406.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histone Methyltransferase Isoforms
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Biological Activity
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PRMT5 |
Chemical Information
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CAS No. 2242753-66-6
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Molecular Weight 406.82
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Formula C18H19ClN4O5
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SMILES
O[C@H]([C@@H]1O)[C@@H](O[C@]1([H])[C@@H](C(C=C2)=CC=C2Cl)O)N3C(NC=N/C4=N\OC)=C4C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)