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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
pyrimidine biosynthesis
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "pyrimidine biosynthesis" in MCE Product Catalog:
6
6 Publications Verification
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Sparfosic acid trisodium is a DNA antimetabolite agent and a potent inhibitor of aspartate transcarbamoyl transferase. Aspartate transcarbamoyl transferase catalyzes the second step of de novo pyrimidine biosynthesis. Sparfosic acid trisodium synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines .
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6 Publications Verification
Cat. No.: HY-112732
CAS No.: 51321-79-0
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Sparfosic acid, a DNA antimetabolite agent, is a potent inhibitor of aspartate transcarbamoyl transferase, the enzyme catalyzing the second step of de novo pyrimidine biosynthesis. Sparfosic acid synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines .
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4 Cited Publications
Cat. No.: HY-N0157A
CAS No.: 68399-76-8
Synonyms: 6-Carboxyuracil zinc; Vitamin B13 zinc
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3 Cited Publications
Synonyms: Cytidine triphosphate; 5'-CTP
3
3 Cited Publications
Cat. No.: HY-W013100
CAS No.: 36051-68-0
Synonyms: Cytidine triphosphate disodium; 5'-CTP disodium
Research Areas:
Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
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3 Cited Publications
Cat. No.: HY-W013707
CAS No.: 81012-87-5
Synonyms: Cytidine triphosphate disodium dihydrate; 5'-CTP disodium dihydrate
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Cytidine-5'-triphosphate disodium dihydrate (5'-CTP disodium dihydrate) is a molecule of high energy, and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation .
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Natural Products Microorganisms Other Diseases Endogenous metabolite Disease Research Fields
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Cat. No.: HY-W013046
CAS No.: 108321-05-7
Synonyms: PRPP pentasodium
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Synonyms: F901318
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Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp. .
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DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway .
Cat. No.: HY-N11189
CAS No.: 34980-65-9
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Cat. No.: HY-125818S3
Purity: 99.0%
Synonyms: Cytidine triphosphate-13C9 dilithium; 5'-CTP-13C9 dilithium
Cat. No.: HY-N0157S1
CAS No.: 1346602-15-0
Synonyms: 6-Carboxyuracil-13C,15N2 monohydrate; Vitamin B13-13C,15N2 monohydrate
Cat. No.: HY-W013100R
CAS No.: 36051-68-0
Synonyms: Cytidine triphosphate disodium (Standard); 5'-CTP disodium (Standard)
Target:
Reference Standards DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
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Cytidine-5'-triphosphate (Cytidine triphosphate) (Standard) disodium is the analytical standard of Cytidine-5'-triphosphate disodium (HY-W013100). This product is intended for research and analytical applications. Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.
Leucyl aminopeptidase, Porcine is a metallopeptidase that cleave N-terminal residues from proteins and peptides. Leucyl aminopeptidase serves as transcriptional repressors to control pyrimidine, alginate and cholera toxin biosynthesis, as well as mediate site-specific recombination events in plasmids and phages .
Cat. No.: HY-146317
CAS No.: 2554623-76-4
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P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor. P1788 induces DNA damage .
Cat. No.: HY-149877
Research Areas:
hDHODH-IN-12 is a potent DHODH inhibitor with an IC50 value of 0.421 μM. DHODH is the rate-limiting enzyme in the de novo synthesis of pyrimidine which is essential in DNA/RNA Synthesis. hDHODH-IN-12 is present in the inner membrane of human mitochondria.hDHODH-IN-12 can be used for the research of lung cancer .
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Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
