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Cat. No.: HY-146317

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P1788

P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor. P1788 induces DNA damage.

For research use only. We do not sell to patients.

CAS No.: 2554623-76-4
Formula: C₁₅H₁₇NO₃
Molecular Weight:259.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

P1788 Chemical Structure

CAS No.: 2554623-76-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor. P1788 induces DNA damage^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 2554623-76-4
Molecular Weight 259.30
Formula C₁₅H₁₇NO₃
SMILES

O=C1OC2(C3=C1C(N(C=C3)C4CC4)=O)CCCCC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hayek S, et al. Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition. Eur J Med Chem. 2020 Jan 15;186:111855. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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