α-D-Ribose-5-phosphate
Based on 3 publication(s) in Google Scholar
α-D-Ribose-5-phosphate is an important intermediate metabolite in the pentose phosphate pathway and in the purine metabolism pathway.
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- CAS No.: 34980-65-9
- Formule: C5H11O8P
- Masse moléculaire:230.11
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Stockage:
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Publications Citing Use of MedChemExpress (MCE) α-D-Ribose-5-phosphate
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Activité biologique
Description
In Vitro
α-D-ribose-5-phosphate (50-700 μM; 4 min) is converted to ribose 1-phosphate by activated Bacillus cereus Bacterial phosphopentomutas (PPM)[1].
α-D-Ribose-5-phosphate (1 mM; 10 min) acts as a substrate for wild-type Bacillus cereus phosphopentomutase[2].
α-D-Ribose-5-phosphate acts as a substrate for purified recombinant Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase (MtPRS)[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 34980-65-9
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Masse moléculaire 230.11
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Formule C5H11O8P
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SMILES
O=P(O)(O)OC[C@@H]1[C@H]([C@H]([C@H](O1)O)O)O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227 -
Cell Rep Med
Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer. [Abstract]2023 Sep 19;4(9):101162. PMID: 37597521 -
Pureté et documentation
Références
[1]. Panosian TD, et al. Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycle. J Biol Chem. 2011;286(10):8043-8054. [Content Brief]
[2]. Iverson TM, et al. Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase. Biochemistry. 2012;51(9):1964-1975. [Content Brief]
[3]. Breda A, et al. Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS?. PLoS One. 2012;7(6):e39245. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
α-D-Ribose-5-phosphate Related Classifications
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