1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Orotidine

Orotidine 

Cat. No.: HY-113226 Purity: ≥95.0%
Handling Instructions

Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants.

For research use only. We do not sell to patients.

Orotidine Chemical Structure

Orotidine Chemical Structure

CAS No. : 314-50-1

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1 mg USD 395 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Extant de novo biosynthetic pathway uses Orotidine 50-monophosphate to synthesize the canonical pyrimidine nucleotides in RNA and DNA. In this context, Orotidine is the only nucleotide that is synthesized through a ‘direct intermolecular nucleosidation’ step, with an attack of the fully-preformed nucleobase (orotic acid) on the activated 5-phosphoribosyl-diphosphate as opposed to the purine nucleotides whose heterocyclic rings are constructed stepwise on the sugar[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

288.21

Formula

C₁₀H₁₂N₂O₈

CAS No.
SMILES

O=C(C(N([[email protected]]1[[email protected]@H]([[email protected]@H]([[email protected]@H](CO)O1)O)O)C2=O)=CC(N2)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References

Purity: ≥95.0%

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Keywords:

OrotidineEndogenous Metabolite50-monophosphatenucleotidebacteriafungiplantsInhibitorinhibitorinhibit

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Orotidine
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