50 Results for "

pyrrolo[2

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "pyrrolo[2" in MCE Product Catalog:

Cat. No.: HY-40351
CAS No.: 3680-69-1
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a nitrogen-containing heterocyclic organic synthesis intermediate that can be used for the synthesis of JAK and PKB/Akt inhibitors [2].
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Cat. No.: HY-40350
CAS No.: 90213-66-4
2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-154823
CAS No.: 2759897-35-1
Purity:  99.23%
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

Gcase activator 2 (compound 14), a pyrrolo[2,3-b]pyrazine, is alos a β-Glucocerebrosidase (GCase) activator (EC50=3.8 μM). Gcase activator 2 induces GCase dimerizatio (both K-type and V-type). And Gcase activator 2 has low metabolic clearance in human and mouse .
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Cat. No.: HY-45448
CAS No.: 1421338-17-1
Target:  

Drug Intermediate

Research Areas:  

Others

4-Chloro-5-nitro-1-tosyl-1H-pyrrolo[2,3-b]pyridine is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-107767
CAS No.: 81307-24-6
Synonyms: DC 81
Research Areas:  

Cancer

Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct [2].
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Cat. No.: HY-42450
CAS No.: 1374639-77-6
Synonyms: (2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol
Target:  

Drug Intermediate

Research Areas:  

Others

2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol ((2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol) is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-42451
CAS No.: 1211443-55-8
Target:  

Drug Intermediate

Research Areas:  

Others

2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-40352
CAS No.: 477600-74-1
Target:  

Drug Intermediate

Research Areas:  

Others

N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-40352B
CAS No.: 1655430-59-3
Target:  

Drug Intermediate

Research Areas:  

Others

N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine dihydrochloride is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-102001
CAS No.: 945490-09-5
Purity:  98.01%
Research Areas:  

Cancer

Tomaymycin DM is a derivative of Tomaymycin (HY-N10174) that belongs to the class of DNA alkylation inhibitors and acts as an effective payload for ADCs. Tomaymycin stabilizes the double-stranded DNA structure, inhibits various DNA processing enzymes, blocks transcription, and ultimately induces DNA strand breaks and apoptosis. Tomaymycin DM can be used in studies related to the development of ADCs targeting multiple cancers including leukemia and ovarian cancer [2].
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Cat. No.: HY-50517
CAS No.: 55052-24-9
Target:  

Drug Intermediate

Research Areas:  

Others

1H-Pyrrolo[2,3-b]pyridine 7-oxide is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-22403
CAS No.: 1240301-66-9
Target:  

Drug Intermediate

Research Areas:  

Others

tert-Butyl 3-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyrrolidine-1-carboxylate is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-152616
CAS No.: 444020-71-7
Research Areas:  

Others

2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-78248
CAS No.: 941685-27-4
4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-30011
CAS No.: 866546-07-8
Synonyms: 5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1H-pyrrolo[2,3-b]pyridine
5-Chloro-7-azaindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-30017
CAS No.: 74420-15-8
3-Bromo-1H-pyrrolo[2,3-b]pyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-77336
CAS No.: 123148-78-7
4-Chloro-5-iodo-1H-pyrrolo[2,3-d]pyrimidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-149636
Purity:  99.82%
Target:  

EGFR CDK VEGFR Apoptosis

Research Areas:  

Cancer

Multi-target kinase inhibitor 2 is a multi-targeted kinase inhibitor, and exhibits activity against EGFR, Her2, VEGFR2, and CDK2 enzymes, with IC50 values of 79 nM, 40 nM,136 nM, and 204 nM, respectively. Multi-target kinase inhibitor 2 shows cytotoxic effects were observed against HepG2, HeLa , MDA-MB-231 and MCF-7, with IC50 of 41, 57, 51 and 59 μM. Multi-target kinase inhibitor 2 induces cell cycle arrest and apoptosis in HepG2 cells .
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Cat. No.: HY-50522
CAS No.: 23612-48-8
Target:  

Drug Intermediate

Research Areas:  

Others

2-Methyl-1H-pyrrolo[2,3-b]pyridine is a heterocyclic organic compound that can be used as a drug intermediate to construct complex molecules, such as BMS-645737, a VEGFR-2 inhibitor .
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Cat. No.: HY-43791
CAS No.: 19393-83-0
Target:  

Drug Intermediate

Research Areas:  

Others

4-Amino-6-bromo-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile is a drug intermediate for synthesis of various active compounds.
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