2759897-35-1
Chemical Structure
Gcase activator 2
- CAS No.: 2759897-35-1
- Formula:C21H24N4O2
- Molecular Weight:364.44
IUPAC Name: 1-(4-(2-(4-methoxyphenyl)-5-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)piperidin-1-yl)ethan-1-one
InChIKey: HEAGFUMRBLFGAD-UHFFFAOYSA-N
SMILES: CC(N1CCC(C2=CC3=NC(C4=CC=C(OC)C=C4)=CN=C3N2C)CC1)=O
Biological Activity: Gcase activator 2 (compound 14), a pyrrolo[2,3-b]pyrazine, is alos a β-Glucocerebrosidase (GCase) activator (EC50=3.8 μM). Gcase activator 2 induces GCase dimerizatio (both K-type and V-type). And Gcase activator 2 has low metabolic clearance in human and mouse[1].
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Gcase activator 2 | 99.62% | Gcase activator 2 (compound 14), a pyrrolo[2,3-b]pyrazine, is alos a β-Glucocerebrosidase (GCase) activator (EC50=3.8 μM). Gcase activator 2 induces GCase dimerizatio (both K-type and V-type). And Gcase activator 2 has low metabolic clearance in human and mouse. | ||||||||||||||||||||
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Keywords