2 Results for "

r8 Bid BH3

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "r8 Bid BH3" in MCE Product Catalog:

Cat. No.: HY-P5327
Target:  

Bcl-2 Family

Research Areas:  

Others

r8 Bid BH3 is a biological active peptide. (The Bid BH3 is a pro-apoptotic member of the 'BH3-only' subset of BCL-2 family proteins that constitute a critical control point in apoptosis. r8BIDBH3 is lethal to human leukemia cell lines that expresse Bcl-2. The Bcl-2 antagonists may have the potential to be efficacious in cancer therapy. Poly-D-arginine (d-isomer as denoted by rrrrrrrr) is fused to the Bid BH3 peptide to facilitate cellular uptake of the peptide.)
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Cat. No.: HY-P11374
Target:  

Bcl-2 Family Apoptosis

Research Areas:  

Cancer

Bid BH3-Gly-r8 is Bid BH3 linked to eight arginine residues. Bid BH3-Gly-r8 shows no difference in apoptotic effects compared to its unmodified peptide homologue. Bid BH3 has high affinity for Bax and Bcl-2. Bid BH3-Gly-r8 can be used in the research of tumors .
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