55 Results for "

rhinovirus

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "rhinovirus" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-N1067
CAS No.: 6754-58-1
Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
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9
9 Cited Publications
Cat. No.: HY-112258
CAS No.: 2059148-82-0
Purity:  99.16%
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC50s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a Kd of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection .
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8
8 Cited Publications
Cat. No.: HY-106161
CAS No.: 223537-30-2
Purity:  99.36%
Synonyms: AG7088
Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC50 of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .
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3
3 Cited Publications
Cat. No.: HY-13784
CAS No.: 124436-59-5
Purity:  99.18%
Synonyms: R77975
Target:  

Enterovirus

Research Areas:  

Infection

Pirodavir is a potent, broad-spectrum picornavirus inhibitor, and is highly active against both group A and group B rhinovirus serotypes. Pirodavir is very potent in a virus yield reduction assay (IC90=2.3 nM).
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2
2 Cited Publications
Cat. No.: HY-112726
CAS No.: 1478364-68-9
Purity:  98.79%
Synonyms: BI-1467335
Target:  

VAP-1 MMP

PXS-4728A is an orally active, selective VAP-1/SSAO inhibitor with an IC50 of 5 nM and a Ki of 175 nM. PXS-4728A inhibits the expression of MMP-9. It reduces cell rolling, adhesion and migration, decreases cell infiltration levels, pro-inflammatory cytokines, chemokines and collagen deposition, and improves pulmonary function. PXS-4728A reduces the formation and progression of atherosclerotic plaques, and decreases blood lipid and blood glucose levels as well as body weight gain. PXS-4728A can be used in research related to chronic obstructive pulmonary disease, cystic fibrosis, acute pulmonary inflammation, acute lung injury, bronchiolitis obliterans syndrome, rhinovirus-exacerbated asthma, sepsis, Klebsiella pneumoniae pulmonary infection and atherosclerosis .
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2
2 Cited Publications
Cat. No.: HY-W011733
CAS No.: 56776-01-3
Synonyms: C-78
Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength . Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation .
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2
2 Cited Publications
Cat. No.: HY-129041
CAS No.: 81262-93-3
Purity:  99.88%
Synonyms: OPC 2009 hydrochloride hemihydrate
Target:  

Adrenergic Receptor

Research Areas:  

Infection Inflammation/Immunology

Procaterol hydrochloride hemihydrate is an orally active β2 adrenoreceptor agonist. Procaterol hydrochloride hemihydrate can be used for the research of asthma .
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1
1 Cited Publications
Cat. No.: HY-P73911
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ICAM1; Epididymis Secretory Sperm Binding Protein; Intercellular Adhesion Molecule 1; Intercellular Adhesion Molecule-1; CD54; Cell Surface Glycoprotein P3.58; BB2; Human rhinovirus Receptor; Major Group rhinovirus Receptor; CD54 Antigen; ICAM-1; P3.58; I
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P80502
Synonyms: ICAM1; Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; CD antigen CD54

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human

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Cat. No.: HY-N1860
CAS No.: 1486-70-0
3-O-Methylquercetin is an inhibitor of cAMP and CGMP-phosphodiesterase (PDE) with IC50 at 13.8 μM and 14.3 μM, respectively. 3-O-Methylquercetin is an inhibitor of β-secretase with an IC50 of 6.5 μM. 3-O-Methylquercetin has a neuroprotective effect against neuronal death caused by oxidative damage. 3-O-Methylquercetin has strong antiviral activity against poliovirus, coxsackie virus and human rhinovirus. 3-O-Methylquercetin has anti-inflammatory and trachea-relaxing effects and can be used in the study of inflammatory diseases and asthma .
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Cat. No.: HY-B0603
CAS No.: 90566-53-3
Fluticasone is an inhaled corticosteroid used for respiratory research. Fluticasone is a Smo agonist with an IC50 value of 99 nM. Fluticasone activates Hedgehog signaling and promotes the proliferation of primary neuronal stem or precursor cells .
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Cat. No.: HY-121527
CAS No.: 1300-94-3
Purity:  98.26%
Amylmetacresol is a phenolic compound with topical antibacterial and antiviral activity. Amylmetacresol works by destroying the protein structure of the virus surface or interfering with the function of the virus lipid membrane. Amylmetacresol inhibits the attachment and replication of respiratory viruses such as human Rhinovirus 1a and influenza virus A, without significant effect on viruses such as HRV8. Amylmetacresol is mainly applied topically to the throat to relieve viral sore throats. Amylmetacresol is more active against enveloped viruses than non-enveloped viruses .
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Cat. No.: HY-P991278

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

ABM-125 is a IL-25 neutralizer and immune response modulator. ABM-125 neutralizes human and mouse IL-25 and blocks type 2 immune activation function. ABM-125 regulates virus-induced inflammatory cytokine expression and increases the expression level of antiviral interferons in rhinovirus-infected asthmatic bronchial epithelial cells. For the isotype control of ABM-125, refer to Human IgG1 kappa, Isotype Control (HY-P99001). ABM-125 is applicable to research related to virus-induced acute asthma exacerbations .
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Cat. No.: HY-106296
CAS No.: 107355-45-3
Purity:  98.14%
Target:  

Enterovirus

Research Areas:  

Infection

WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections .
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Cat. No.: HY-N14780
CAS No.: 544712-82-5
Synonyms: (+)-Pochonin D
Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affects the homeostasis, folding and assembly processes of viral proteins, and reduces the replication capacity of viruses. Pochonin D is a copper ion carrier that can induce cuproptosis in triple-negative breast cancer cells by targeting PRDX1. Pochonin D reduces the infiltration of inflammatory cells, decreases the secretion of inflammatory cytokines such as TNF-α and IL-1β, and alleviates inflammatory responses. Pochonin D is a promising candidate for research on human rhinovirus (HRV) infection and cancer .
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Cat. No.: HY-N12982
CAS No.: 21391-99-1
α-Calacorene is a sesquiterpene that can be isolated from Réunion vetiver oil .
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Cat. No.: HY-W742100
CAS No.: 465-22-5
Target:  

Enterovirus

Research Areas:  

Infection

Scillarenin is a plant bufadienolide and cardiotonic agent. Scillarenin selectively inhibits replication of picornaviruses, in particular, rhinovirus .
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Cat. No.: HY-P10975
CAS No.: 2484874-12-4
Research Areas:  

Infection

P9R is an antiviral peptide. P9R has broad-spectrum antiviral activities against the coronaviruses (SARS-CoV-2, MERS-CoV and SARS-CoV), A(H1N1)pdm09, A(H7N9) virus, and rhinovirus. P9R directly binds to viruses and inhibits virus-host endosomal acidification. P9R significantly protects mice from A(H1N1)pdm09 infection without generating drug-resistant virus. P9R can be used for pH-dependent respiratory viruses research .
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Cat. No.: HY-175557
CAS No.: 2411491-16-0
Target:  

PI4K Enterovirus

Research Areas:  

Infection

PI4K-IN-2 (Compound 30) is a highly selective type III phosphatidylinositol 4-kinase β (PI4KB) inhibitor (IC50=0.015 μM). PI4K-IN-2 is promising for research of human rhinovirus (HRV) .
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Cat. No.: HY-N1067R
CAS No.: 6754-58-1
Xanthohumol (Standard) is the analytical standard of Xanthohumol. This product is intended for research and analytical applications. Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
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