103 Results for "

riboside

" in MedChemExpress (MCE) Product Catalog:
Products (103)

103 Results for "riboside" in MCE Product Catalog:

226
AICAR
AICAR
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226 Publications Verification
Cat. No.: HY-13417
CAS No.: 2627-69-2
Purity:  99.98%
Synonyms: Acadesine; AICA riboside
Category:  

Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

AMPK Autophagy YAP Mitophagy Endogenous Metabolite

AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR is also an autophagy, YAP and mitophagy inhibitor. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR inhibits autophagy through a mechanism independent of AMPK activity .
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226
AICAR phosphate
AICAR phosphate
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226 Publications Verification
Cat. No.: HY-13417A
CAS No.: 681006-28-0
Purity:  99.98%
Synonyms: Acadesine phosphate; AICA riboside phosphate
Category:  

Alkaloids Animals Other Alkaloids Disease Research Fields Cancer

Target:  

AMPK Autophagy YAP Mitophagy Endogenous Metabolite

AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy, YAP and mitophagy inhibitor .
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28
Nicotinamide riboside chloride
Nicotinamide riboside chloride
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28 Cited Publications
Cat. No.: HY-123033A
CAS No.: 23111-00-4
Purity:  99.90%
Category:  

Alkaloids Neurological Disease Animals Anti-aging Pyridine Alkaloids Metabolic Disease Disease Research Fields

Target:  

Sirtuin Endogenous Metabolite

Nicotinamide riboside Chloride, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease .
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28
Nicotinamide riboside malate
Nicotinamide riboside malate
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28 Cited Publications
Cat. No.: HY-123033C
CAS No.: 2415659-01-5
Purity:  98.04%
Category:  

Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Sirtuin Endogenous Metabolite

Nicotinamide riboside malate, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside malate is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside malate reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease .
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28
Nicotinamide riboside tartrate
Nicotinamide riboside tartrate
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28 Cited Publications
Cat. No.: HY-123033B
CAS No.: 2415657-86-0
Category:  

Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Sirtuin Endogenous Metabolite

Nicotinamide riboside tartrate, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside tartrate is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside tartrate reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease .
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18
Adenosine
Adenosine
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18 Cited Publications
Cat. No.: HY-B0228
CAS No.: 58-61-7
Synonyms: Adenine riboside; D-Adenosine
Category:  

Natural Products Microorganisms Marine natural products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Environmental Pollutants Autophagy Nucleoside Antimetabolite/Analog Endogenous Metabolite Apoptosis

Adenosine (Adenine riboside), a ubiquitous and BBB-permeable endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
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9
5,6-Dichlorobenzimidazole riboside
5,6-Dichlorobenzimidazole riboside
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9 Cited Publications
Cat. No.: HY-14392
CAS No.: 53-85-0
Purity:  99.89%
Synonyms: DRB
Target:  

CDK Apoptosis

Research Areas:  

Cancer

5,6-Dichlorobenzimidazole riboside (DRB) is a nucleoside analog that inhibits several carboxyl-terminal domain kinases, including casein kinase II and cell cycle-dependent kinases (CDK). 5, 6-dichlorobenzimidazole riboside has antitumor activity. 5, 6-dichlorobenzimidazole riboside can induce apoptosis .
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8
Cytidine
Cytidine
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8 Cited Publications
Cat. No.: HY-B0158
CAS No.: 65-46-3
Synonyms: Cytosine β-D-riboside; Cytosine-1-β-D-ribofuranoside
Category:  

Human Gut Microbiota Metabolites Natural Products other families Microorganisms Animals Disease markers Nervous System Disorder Plants Endogenous metabolite

Target:  

Nucleoside Antimetabolite/Analog Endogenous Metabolite

Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
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3
Kinetin riboside
Kinetin riboside
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3 Cited Publications
Cat. No.: HY-101055
CAS No.: 4338-47-0
Purity:  99.88%
Synonyms: N6-Furfuryladenosine
Target:  

Apoptosis

Research Areas:  

Cancer

Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC50 of 2.5 μM.
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3
Allopurinol riboside
Allopurinol riboside
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3 Cited Publications
Cat. No.: HY-101397
CAS No.: 16220-07-8
Purity:  99.05%
Category:  

Infection Alkaloids Endogenous metabolite Disease Research Fields Indole Alkaloids

Target:  

Parasite Drug Metabolite Endogenous Metabolite

Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites.
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2
SBI-797812
SBI-797812
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2 Cited Publications
Cat. No.: HY-126255
CAS No.: 2237268-08-3
Purity:  99.88%
Target:  

NAMPT

Research Areas:  

Metabolic Disease

SBI-797812 is an orally active nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 shifts NAMPT to NMN formation, increases NAMPT affinity for ATP, stabilizes phosphorylated NAMPT, promotes consumption of the pyrophosphate by-product, and blunts feedback inhibition by NAD +. SBI-797812 increases intracellular nicotinamide mononucleotide (NMN) and elevates liver NAD + in mice .
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1
N6-(4-Hydroxybenzyl)adenosine
N6-(4-Hydroxybenzyl)adenosine
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1 Cited Publications
Cat. No.: HY-18775
CAS No.: 110505-75-4
Synonyms: Para-topolin riboside
Target:  

Nucleoside Transporters Adenosine Receptor P2Y Receptor

Research Areas:  

Neurological Disease

N6-(4-Hydroxybenzyl) adenosine (Para-topolin riboside) is an equilibrative nucleoside transporter 1 (ENT1) inhibitor and a selective agonist of adenosine A2a receptor (A2aR), and also exhibits activity against P2Y12 receptor. N6-(4-Hydroxybenzyl) adenosine reduces ethanol intake and preference, attenuates operant conditioning-induced ethanol place preference, decreases the value of ethanol-related rewards, and inhibits collagen-induced platelet aggregation. N6-(4-Hydroxybenzyl) adenosine can be used in studies related to alcohol use disorder .
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Nicotinic acid riboside
Nicotinic acid riboside
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Cat. No.: HY-W104368
CAS No.: 17720-18-2
Category:  

Alkaloids Agrostidoideae Pyridine Alkaloids Metabolic Disease Plants Disease Research Fields Triticum aestivum L.

Target:  

Endogenous Metabolite

Nicotinic acid riboside is a NAD + precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD + metabolism .
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Nicotinamide riboside
Nicotinamide riboside
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Cat. No.: HY-123033
CAS No.: 1341-23-7
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Animals Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Sirtuin Endogenous Metabolite

Nicotinamide riboside, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities . Nicotinamide riboside reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease .
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Dihydronicotinamide riboside
Dihydronicotinamide riboside
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Cat. No.: HY-W614507
CAS No.: 19132-12-8
Target:  

NADPH Oxidase Apoptosis Bcl-2 Family

Research Areas:  

Metabolic Disease Cancer

Dihydronicotinamide riboside is a potent NAD + concentration enhancer. Dihydronicotinamide riboside modulates targets BAX, PUMA, NQO2, and IκB kinase. Dihydronicotinamide riboside mediates apoptosis, induces pro-oxidant activity, mitochondrial dysfunction, metabolic dysregulation, redox modulation, and pro-inflammatory M1 phenotype induction. Dihydronicotinamide riboside increases intracellular and mitochondrial NAD + levels, maintains cell survival against NAD +-depleting genotoxins. Dihydronicotinamide riboside can be used for the research of hepatocellular carcinoma .
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AICA-riboside, 5′-phosphate
AICA-riboside, 5′-phosphate
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Cat. No.: HY-134356
CAS No.: 3031-94-5
Purity:  99.95%
Synonyms: AICAR-5'-MP
Category:  

Human Gut Microbiota Metabolites Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

AICA-riboside, 5′-phosphate is AICA riboside with a phosphate group. The functions of AICA riboside include: 1) conversion into AMP mimetic to selectively activate AMPK; 2) competition with adenosine for the uptake of nucleoside transporters, reversible blocking of adenosine reuptake, increasing extracellular adenosine concentration, and indirectly activating adenosine A1 receptors. AICA riboside is involved in metabolic regulation (promoting catabolism and inhibiting anabolism) and adenosine-dependent neuroprotection (inhibiting excitatory synaptic transmission). AICA riboside can be used in the study of metabolic diseases (such as diabetes and obesity) and neurological diseases (such as ischemia and epilepsy), and has central nervous system protective activity .
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Adenosine-15N5
Adenosine-15N5
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Cat. No.: HY-B0228S11
CAS No.: 168566-57-2
Synonyms: Adenine riboside-15N5; D-Adenosine-15N5
Adenosine- 15N5 (Adenine riboside- 15N5; D-Adenosine- 15N5) is the 15N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
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Adenosine-13C5
Adenosine-13C5
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Cat. No.: HY-B0228S1
CAS No.: 159496-13-6
Synonyms: Adenine riboside-13C5; D-Adenosine-13C5
Adenosine- 13C5 is the 13C labeled Adenosine . Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
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AICAR (Standard)
AICAR (Standard)
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Cat. No.: HY-13417R
CAS No.: 2627-69-2
Synonyms: Acadesine (Standard); AICA riboside (Standard)
Category:  

Human Gut Microbiota Metabolites Natural Products Endogenous metabolite

Target:  

Reference Standards AMPK Autophagy YAP Mitophagy Endogenous Metabolite

AICAR (Standard) is the analytical standard of AICAR. This product is intended for research and analytical applications. AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor .
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Adenosine (Standard)
Adenosine (Standard)
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Cat. No.: HY-B0228R
CAS No.: 58-61-7
Synonyms: Adenine riboside (Standard); D-Adenosine (Standard)
Category:  

Natural Products Microorganisms Endogenous metabolite

Target:  

Reference Standards Nucleoside Antimetabolite/Analog Autophagy Apoptosis Endogenous Metabolite

Adenosine (Standard) is the analytical standard of Adenosine. This product is intended for research and analytical applications. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
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