17720-18-2
17720-18-2
Chemical Structure
Nicotinic acid riboside
- CAS No.: 17720-18-2
- Formula:C11H13NO6
- Molecular Weight:255.23
IUPAC Name: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate
InChIKey: PUEDDPCUCPRQNY-ZYUZMQFOSA-N
SMILES: [O-]C(C1=C[N+]([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=CC=C1)=O
Biological Activity: Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nicotinic acid riboside | 99.90% | Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism. | ||||||||||||||||||||
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Nicotinic acid riboside (Standard) | ≥98% | Nicotinic acid riboside (Standard) is the analytical standard of Nicotinic acid riboside (HY-W104368). This product is intended for research and analytical applications. Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism. | ||||||||||||||||||||
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Nicotinic acid riboside-d4 | 98.65% | Nicotinic acid riboside-d4 is the deuterium labeled Nicotinic acid riboside (HY-W104368). Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism. | ||||||||||||||||||||
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References
- [1]. Sasaki Y, et al. Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection. Exp Neurol. 2021;345:113842. [Content Brief]
- [2]. Bogan KL, et al. Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside [published correction appears in J Biol Chem. 2010 Jan 29;285(5):3524]. J Biol Chem. 2009;284(50):34861-34869. [Content Brief]
