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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
rigid
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "rigid" in MCE Product Catalog:
4
2
2 Cited Publications
Synonyms: CB7; Carrier CB7
1
Synonyms: MECPP
Target:
Research Areas:
Mono (5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of di-(2-ethylhexyl) phthalate (DEHP). Di (2-ethylhexyl) phthalate is the primary plasticizer added to rigid polyvinyl chloride (PVC), and it imparts flexibility, temperature resistance, optical transparency, strength, and kink resistance .
Cat. No.: HY-W090294
CAS No.: 198-55-0
Synonyms: Peri-dinaphthalene (purified by sublimation)
Cat. No.: HY-W040206
CAS No.: 83164-33-4
Research Areas:
Diflufenican is a Herbicide. Diflufenican inhibits phytoene desaturase (PDS) in the carotenoid synthesis pathway. Diflufenican suppresses the production of PDS, blocks carotenoid biosynthesis, thereby inducing chlorophyll destruction and cell membrane rupture, and ultimately causes the death of broadleaf weeds. The combination of Diflufenican and Flufenacet can be used to control Lolium rigidum populations resistant to ALS/ACCase .
Cat. No.: HY-W074648
CAS No.: 1239602-35-7
Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium .
Cat. No.: HY-46871
CAS No.: 93004-48-9
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3,9-Dimethyl-3,9-diazaspiro[5.5]undecane is a rigid PROTAC linker can be used in the synthesis of PROTACs, such as FIP22 (HY-175764). FIP22 is a potent and selective IRAK4 PROTAC degrader with anti- atopic dermatitis activity .
Cat. No.: HY-W025438
CAS No.: 103285-22-9
Research Areas:
5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a 2'-O-methyluridine derivative bearing a 5'-O-(4,4'-dimethoxytrityl) protecting group.5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine serves as a starting material for synthesis of a conformationally rigid cyclic uridylic acid derivative .
Cat. No.: HY-157566
CAS No.: 2520105-60-4
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Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride is a functionalized cerebellar ligand for PROTAC development, combining E3 ligand and terminal piperidine for subsequent chemical reactions. A protein degradant with a rigid connector is generated .
Cat. No.: HY-W008721
CAS No.: 2420-87-3
Synonyms: AIDA
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Research Areas:
UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 μM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis .
Cat. No.: HY-151829
CAS No.: 2616562-74-2
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Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-177767
CAS No.: 960294-74-0
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Research Areas:
EY-CBS is a synthetic and rigid cross linker. EY-CBS reacts selectively with cysteines in a-helices, to stabilize the connecting helix. EY-CBS can be used for the study of the structural stability of protein polypeptides .
Cat. No.: HY-W180804
CAS No.: 55804-67-6
Synonyms: Coumarin 521
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Research Areas:
Coumarin 334 (Coumarin 521) is a laser dye with rigid structure .
Cat. No.: HY-W763591B
CAS No.: 24991-55-7
Cat. No.: HY-W763591C
CAS No.: 24991-55-7
Cat. No.: HY-W763591A
CAS No.: 24991-55-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
