24 Results for "

sialidase

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "sialidase" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-125798
CAS No.: 24967-27-9
Purity:  ≥98.0%
Synonyms: Neu5Ac2en; DANA
Target:  

Influenza Virus

Research Areas:  

Infection

N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity .
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1
1 Cited Publications
Cat. No.: HY-P2988
CAS No.: 9001-67-6
Synonyms: Exo-α-sialidase
Target:  

Sialyltransferase

Research Areas:  

Infection

Neuraminidase, Microorganism (Exo-α-sialidase) is an exosialidase, is often used in biochemical studies. Neuraminidase cleaves α-ketosidic linkage between the sialic (N-acetylneuraminic) acid and an adjacent sugar residue. Neuraminidase, derived from mucosal pathogens, is a virulence factor that modifies the host's response to infection .
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1
1 Cited Publications
Cat. No.: HY-W020790
CAS No.: 98603-84-0
Synonyms: sLeX
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) . Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability?to inhibits CD62-mediated neutrophil recruitment to sites of inflammation .
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Cat. No.: HY-E70097
Target:  

Sialyltransferase

Research Areas:  

Others

Sialidase (α2-3-6-8-9) is a broadly specific sialidase that cuts linear and branched non-reducing terminal sialic acid residues from glycoproteins, glycopeptides, and oligosaccharides. Sialidase (α2-3-6-8-9) can be used for in vitro and in vivo polysaccharide analysis and characterization as well as complete glycoprotein remodeling .
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Cat. No.: HY-122351A
CAS No.: 714229-20-6
Purity:  99.66%
Target:  

Taste Receptor

Research Areas:  

Others

Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
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Cat. No.: HY-N1470
CAS No.: 78708-33-5
Plantagoside is a flavanone glucoside found in Plantago asiatica seeds, acting as a specific non-competitive α-mannosidase inhibitor with IC50 values of 5 μM and a Ki of 2.7 μM (jack bean). Plantagoside suppresses antibody response and Concanavalin A (HY-P2149)-induced lymphocyte proliferation in mouse spleen cells. Plantagoside inhibits the Maillard reaction, advanced glycation end product formation, and glycation-dependent protein-protein cross-link formation. Plantagoside can be used for the research of diabetes .
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Cat. No.: HY-145533
CAS No.: 153666-19-4
Purity:  99.90%
Synonyms: KDN
Research Areas:  

Others

3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a type of sialic acid. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid can be hydrolyzed by sialidase from the loach (Misgurnus fossilis) .
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Cat. No.: HY-E70043
CAS No.: 2170331-76-5
Synonyms: sialidase isoenzyme S; Ausialidase S
Target:  

Sialyltransferase

Research Areas:  

Metabolic Disease

Ganglioside sialidase (AuSialidase S) is an endogenous metabolite. Ganglioside sialidases have been implicated in neuronal differentiation processes, including neurite outgrowth .
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Cat. No.: HY-N7529
CAS No.: 54795-58-3
Research Areas:  

Others

Siastatin B is an effective broad-spectrum glycosidase inhibitor that can effectively inhibit the activities of sialidase, β-D-glucuronidase, N-acetyl-glucosaminidase, β-glucuronidase, and human heparinase .
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Cat. No.: HY-E70073
CAS No.: 2170331-76-5
Synonyms: sialidase isoenzyme M2; Ausialidase M2
Research Areas:  

Others

Ganglioside sialidase (AuSialidase M2) from Arthrobacter ureafaciens. Ganglioside sialidase is a highly specific N-acetylneuraminidase. Ganglioside sialidase can hydrolyze the internal sialic acid of GM1 under optimal condition with sodium cholate .
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Cat. No.: HY-E70019
Target:  

Sialyltransferase

Research Areas:  

Metabolic Disease

alpha-2-3,6-sialidase (BiNanH2) is a sialyltransferase, is often used in biochemical studies. alpha-2-3,6-sialidase (BiNanH2) catalyzes α-2,3/2,6-sialyltransfer from CMP-Neu5Ac to galactoside acceptors .
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Cat. No.: HY-145533A
Purity:  ≥95.0%
Synonyms: KDN sodium
3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid sodium (KDN sodium) is a type of sialic acid. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid sodium can be hydrolyzed by sialidase from the loach (Misgurnus fossilis) .
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Cat. No.: HY-P990988
CAS No.: 2891502-37-5

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

HY-P990988 is an Sialidase-2-targeting Fusion Protein .
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Cat. No.: HY-172951
Target:  

Parasite

Research Areas:  

Infection

Antitrypanosomal agent 23 is an antitrypanosomal agent. Antitrypanosomal agent 23 has activity against intracellular amastigotes of T. cruzi in LLC-MK2 and C2C12 cells (IC50: 0.10 and 0.11 μM). Antitrypanosomal agent 23 is a weak inhibitor of Recombinant trans-sialidase from T. cruzi (TcTS) (IC50: 1.1 mM) .
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Cat. No.: HY-122351
CAS No.: 245650-17-3
Research Areas:  

Others

Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
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Cat. No.: HY-122351AR
CAS No.: 714229-20-6
Research Areas:  

Others

Advantame (Standard) is the analytical standard of Advantame. This product is intended for research and analytical applications. Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
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Cat. No.: HY-P74732
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NEU1; G9 sialidase; Prev. NEU; Neuraminidase 1 (Lysosomal sialidase); sialidase-1; Exo-Alpha-sialidase; N-Acetyl-Alpha-Neuraminidase 1; Neurominidase; Acetylneuraminyl Hydrolase; Neuraminidase; Lysosomal sialidase; SIAL1; sialidase 1 (Lysosomal sialidase)
Species:  
Source:  
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Cat. No.: HY-P77073
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: sialidase; Neuraminidase; nedA
Species:  
Source:  
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Cat. No.: HY-P71310
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NEU1; G9 sialidase; Prev. NEU; Neuraminidase 1 (Lysosomal sialidase); sialidase-1; Exo-Alpha-sialidase; N-Acetyl-Alpha-Neuraminidase 1; Neurominidase; Acetylneuraminyl Hydrolase; Neuraminidase; Lysosomal sialidase; SIAL1; sialidase 1 (Lysosomal sialidase)
Species:  
Source:  
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Cat. No.: HY-P702578
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NEU2; sialidase 2 (Cytosolic sialidase); Neuraminidase 2; Cytosolic sialidase; N-Acetyl-Alpha-Neuraminidase 2; sialidase-2; SIAL2; Neuraminidase 2 (Cytosolic sialidase)
Species:  
Source:  
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