Copy Link Print Information

Neuraminidase Protein, C.perfringens (His)

Customer Review

Based on 1 Customer Validation

Neuraminidase is a subtype of sialidase associated with the pathogenic potential of microbial infections.As an enzyme, neuraminidase plays a crucial role in catalyzing the removal of terminal sialic acid residues from glycoproteins and glycolipids.Neuraminidase Protein, C.perfringens (His) is the recombinant Virus-derived Neuraminidase protein, expressed by E.coli , with N-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Virus
  • Source: E. coli
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Neuraminidase Protein, C.perfringens (His) Product Image
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
Data Download

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Biological Activity

Description

Neuraminidase is a subtype of sialidase associated with the pathogenic potential of microbial infections.As an enzyme, neuraminidase plays a crucial role in catalyzing the removal of terminal sialic acid residues from glycoproteins and glycolipids.Neuraminidase Protein, C.perfringens (His) is the recombinant Virus-derived Neuraminidase protein, expressed by E.coli , with N-His labeled tag.

Background

Neuraminidase is a subtype of sialidases that has been linked to potential pathogenicity in microbial infections. As an enzyme, neuraminidase plays a crucial role in catalyzing the removal of terminal sialic acid residues from glycoproteins and glycolipids. This activity allows the virus or bacteria to facilitate its spread within the host by promoting the release of newly formed viral particles or by enhancing its ability to adhere to and invade host cells. Neuraminidase is considered a critical virulence factor in various pathogens and is targeted by antiviral drugs to inhibit its enzymatic activity and hinder the progression of infection. Understanding the functions and mechanisms of neuraminidase is crucial for developing effective strategies to combat microbial infections.

Verified Bioactivity

Measured by its ability to cleave a fluorogenic substrate, 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid. The specific activity is 150,000 pmoles/min/μg .

Technical Parameters

  • Species Virus
  • Source E. coli
  • Tag N-His
  • Accession

    P10481 (C2-Q382)

  • Gene ID
    /
  • Molecular Construction
    • N-term
    • His
    • Neuraminidase (C2-Q382)
      Accession # P10481
    • C-term
  • Protein Length

    Full Length

  • Synonyms

    NEU1; G9 Sialidase; Prev. NEU; Neuraminidase 1 (Lysosomal Sialidase); Sialidase-1; Exo-Alpha-Sialidase; N-Acetyl-Alpha-Neuraminidase 1; Neurominidase; Acetylneuraminyl Hydrolase; Neuraminidase; Lysosomal Sialidase; SIAL1; Sialidase 1 (Lysosomal Sialidase)

  • AA Sequence

    CNKNNTFEKNLDISHKPEPLILFNKDNNIWNSKYFRIPNIQLLNDGTILTFSDIRYNGPDDHAYIDIASARSTDFGKTWSYNIAMKNNRIDSTYSRVMDSTTVITNTGRIILIAGSWNTNGNWAMTTSTRRSDWSVQMIYSDDNGLTWSNKIDLTKDSSKVKNQPSNTIGWLGGVGSGIVMDDGTIVMPAQISLRENNENNYYSLIIYSKDNGETWTMGNKVPNSNTSENMVIELDGALIMSTRYDYSGYRAAYISHDLGTTWEIYEPLNGKILTGKGSGCQGSFIKATTSNGHRIGLISAPKNTKGEYIRDNIAVYMIDFDDLSKGVQEICIPYPEDGNKLGGGYSCLSFKNNHLGIVYEANGNIEYQDLTPYYSLINKQ

  • Predicted Molecular Mass

    43.6 kDa

  • Molecular Weight

    Approximately 40 kDa, based on SDS-PAGE under reducing conditions.

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Solution

Formulation

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
=
Concentration (final) Concentration (final)
×
Volume (final) Volume (final)
The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • Neuraminidase Protein, C.perfringens (His) Product Image
    1/16
  • Neuraminidase Protein, C.perfringens (His) Product Image