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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
spermine
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "spermine" in MCE Product Catalog:
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10
8
8 Cited Publications
Synonyms: 1-Naphthylacetyl spermine trihydrochloride
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Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
8
8 Cited Publications
Synonyms: 1-Naphthylacetyl spermine
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Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
6
6 Cited Publications
Synonyms: Diethylnorspermine tetrahydrochloride; DENSPM tetrahydrochloride; BENSPM tetrahydrochloride
N1, N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) is a potent anticancer agent. N1,N11-Diethylnorspermine tetrahydrochloride activates polyamine catabolism and downregulates mTOR protein. N1,N11-Diethylnorspermine tetrahydrochloride induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1,N11-Diethylnorspermine tetrahydrochloride kills glioblastoma multiforme (GBM) through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production .
3
3 Cited Publications
Cat. No.: HY-Q36392
CAS No.: 326923-09-5
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JNJ-9350, a chemical probe, is an inhibitor of spermine oxidase (SMOX) with an IC50 value of 0.01 μM. JNJ-9350 also inhibits polyamine oxidase (PAO) with an IC50 value of 0.79 μM. JNJ-9350 can be used for the research of cancer .
2
2 Cited Publications
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Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing .
2
2 Cited Publications
Cat. No.: HY-W015514
CAS No.: 3312-60-5
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N-(3-Aminopropyl)cyclohexylamine, a cyclohexylamine derivative, acts as a selective and competitive inhibitor of spermine synthase. N-(3-Aminopropyl)cyclohexylamine can be used for the research of neurological diseases .
1
1 Cited Publications
Cat. No.: HY-N2393
CAS No.: 164991-67-7
1
1 Cited Publications
Cat. No.: HY-N2392
CAS No.: 75288-96-9
1
1 Cited Publications
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Spermine(N3BBB) is a tri-Boc-protected azido-spermine reagent used for multi-functionalization of pseudo-glycodendrimers via click reaction .
Cat. No.: HY-B1777AS
CAS No.: 1173022-85-9
Cat. No.: HY-W654342
Synonyms: NSC 268508-d20; Neuridine-d20
Synonyms: SBP-101
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Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers .
Cat. No.: HY-149037A
Purity: 98.60%
Synonyms: N4-spermine cholesteryl carbamate pentahydrochloride
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JNJ-1289 is a potent, selective, competitive and allosteric human spermine oxidase (hSMOX) inhibitor (IC50: 50 nM). JNJ-1289 can be used in the research of polyamine catabolism, inflammation and cancers .
Cat. No.: HY-113374A
CAS No.: 77928-71-3
Synonyms: DiAcSpm dihydrochloride
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Synonyms: spermine(HHHN3) trihydrochloride
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N1-Azido-spermine [Spermine(HHHN3)] trihydrochloride is a click chemistry agent containing azide. N1-Azido-spermine trihydrochloride contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. N1-Azido-spermine trihydrochloride can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
