25 Results for "

thiol protease

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "thiol protease" in MCE Product Catalog:

161
161 Publications Verification
Cat. No.: HY-B0496
CAS No.: 329-98-6
Synonyms: Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride
Research Areas:  

Neurological Disease

PMSF (Phenylmethylsulfonyl fluoride) is a nonspecific and irreversible serine proteases inhibitor. PMSF inhibits some thiol proteases, non-protease enzymes, and acetylcholinesterase. PMSF can be used to prepare protein extracts from tissue and cell lysates .
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4
4 Cited Publications
Cat. No.: HY-160225
Research Areas:  

Inflammation/Immunology

ISD sodium is an interferon-stimulatory DNA, a 45 bp non-CpG double-stranded oligonucleotide derived from the genome of Listeria monocytogenes. ISD sodium potently induces type I interferon production via the cGAS‑STING‑TBK1‑IRF3 pathway .
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2
2 Cited Publications
Cat. No.: HY-15941
CAS No.: 27072-45-3
Synonyms: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
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Cat. No.: HY-P2895
CAS No.: 9028-00-6
Synonyms: Clostridiopeptidase B
Target:  

Endogenous Metabolite

Research Areas:  

Others

Clostripain (Clostridiopeptidase B) is a thiol protease isolated from Clostridium histolyticum. Clostripain exhibits proteolytic activity as well as amidase-esterase activity. The specificity of Clostripain is primarily restricted to arginine residues, but it also shows minor hydrolytic activity toward most lysine-containing substrates. Clostripain catalyzes the ammonolysis of Carbobenzoxyarginyl methyl ester to generate various dipeptides .
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Cat. No.: HY-E70364
CAS No.: 1892548-76-3
Research Areas:  

Inflammation/Immunology

IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .
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Cat. No.: HY-P10828
CAS No.: 1260620-30-1
Target:  

Virus Protease

Research Areas:  

Infection Inflammation/Immunology

MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
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Cat. No.: HY-N14193
CAS No.: 106396-24-1
Estatin B is a thiol protease inhibitor found by the Thermophilic Bacterium M4323, which is specific to thiol proteases such as papain, fig protease, and bromelain. Estatin B inhibits the production of IgE antibodies but not IgG in mice .
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Cat. No.: HY-120288
CAS No.: 160825-49-0
Target:  

Cathepsin

Research Areas:  

Infection Metabolic Disease

AM4299B is an inhibitor for thiol protease. AM4299B inhibits bovine spleen cathepsin B, human kidney cathepsin L and papain with IC50s of 0.7, 0.5 and 20 μM, respectively. AM4299B can be used in research in osteoporosis, and has potential to be used as an antiparasitic agent .
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Cat. No.: HY-152919
CAS No.: 2387738-43-2
Target:  

ADC Linkers

Research Areas:  

Cancer

Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.
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Cat. No.: HY-P703416
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Ufm1-specific protease 1; UFSP1; Homo sapiens; Human; Hydrolase; protease; thiol protease
Species:  
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Cat. No.: HY-P703430
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ubiquitin-like-specific protease 1; ulp1; Schizosaccharomyces pombe (strain 972 / ATCC 24843); Fission yeast; Hydrolase; protease; thiol protease
Species:  
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Cat. No.: HY-P703433
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Sortase A; Surface protein sorting A; srtA; Staphylococcus aureus (strain NCTC 8325 / PS 47); Hydrolase; protease; thiol protease; 3.4.22.70
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Cat. No.: HY-P703434
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Sortase A; Surface protein sorting A; srtA; Staphylococcus aureus (strain NCTC 8325 / PS 47); Hydrolase; protease; thiol protease; 3.4.22.70
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Cat. No.: HY-P703548
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Avian infectious bronchitis virus (strain M41); IBV; pp1a; Hydrolase; Lyase; protease; RNA-binding; thiol protease
Species:  
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Cat. No.: HY-P703274
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ubiquitin carboxyl-terminal hydrolase 3; Deubiquitinating enzyme 3; Ubiquitin thioesterase 3; Ubiquitin-specific-processing protease 3; USP3; Homo sapiens; Human; Chromatin regulator; Hydrolase; protease; thiol protease; 3.4.19.12
Species:  
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Cat. No.: HY-P703536
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:  
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Cat. No.: HY-P703539
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:  
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Cat. No.: HY-P703534
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:  
Source:  
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Cat. No.: HY-P703535
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:  
Source:  
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Cat. No.: HY-P703537
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:  
Source:  
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