CDKN1A - cyclin dependent kinase inhibitor 1A Gene

Also Known as P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1026

About CDKN1A

Cytogenetic location: 6p21.2 Genomic coordinates (GRCh38): 6:36,676,463-36,687,332 (from NCBI)

This gene has 8 transcripts (splice variants), 196 orthologues, 2 paralogues and is associated with 77 phenotypes. Ubiquitous expression in colon (RPKM 71.4), gall bladder (RPKM 68.8) and 24 other tissues.

Summary

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA Polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of Apoptosis following Caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Sep 2015]

CDKN1A Products (10)

mRNA Protein Name
NM_000389.5 NP_000380.1 cyclin-dependent kinase inhibitor 1 isoform 1
NM_001220777.2 NP_001207706.1 cyclin-dependent kinase inhibitor 1 isoform 1
NM_001220778.2 NP_001207707.1 cyclin-dependent kinase inhibitor 1 isoform 1
NM_001291549.3 NP_001278478.1 cyclin-dependent kinase inhibitor 1 isoform 2
NM_001374509.1 NP_001361438.1 cyclin-dependent kinase inhibitor 1 isoform 2
NM_001374510.1 NP_001361439.1 cyclin-dependent kinase inhibitor 1 isoform 3
NM_001374511.1 NP_001361440.1 cyclin-dependent kinase inhibitor 1 isoform 4
NM_001374512.1 NP_001361441.1 cyclin-dependent kinase inhibitor 1 isoform 5
NM_001374513.1 NP_001361442.1 cyclin-dependent kinase inhibitor 1 isoform 1
NM_078467.3 NP_510867.1 cyclin-dependent kinase inhibitor 1 isoform 1
Molecular Function GO Annotation Evidence References Source
enables cyclin-dependent protein kinase activating kinase activity IDA
IDA: Inferred from direct assay
9106657 GOA
enables cyclin-dependent protein serine/threonine kinase inhibitor activity IDA
IDA: Inferred from direct assay
11463845 GOA
enables molecular function activator activity IMP
IMP: Inferred from mutant phenotype
17553787 GOA
enables molecular function inhibitor activity IDA
IDA: Inferred from direct assay
8876165 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
8756624 GOA
enables protein kinase binding IPI
IPI: Inferred from physical interaction
8876165 GOA
enables protein kinase inhibitor activity IMP
IMP: Inferred from mutant phenotype
8876165 GOA
enables protein sequestering activity EXP
EXP: Inferred from Experiment
11595739 GOA
enables protein sequestering activity IMP
IMP: Inferred from mutant phenotype
11595739 GOA
enables protein serine/threonine kinase binding IPI
IPI: Inferred from physical interaction
11463845 GOA
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
8876165 GOA
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
23026136 GOA
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IMP
IMP: Inferred from mutant phenotype
20160708 GOA
involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IDA
IDA: Inferred from direct assay
15149599 GOA
involved in Ras protein signal transduction IEP
IEP: Inferred from expression pattern
9054499 GOA
involved in cellular response to amino acid starvation IMP
IMP: Inferred from mutant phenotype
26102367 GOA
involved in cellular response to cell-matrix adhesion IMP
IMP: Inferred from mutant phenotype
17553787 GOA
involved in cellular response to ionizing radiation IMP
IMP: Inferred from mutant phenotype
20160708 GOA
acts upstream of cellular senescence IMP
IMP: Inferred from mutant phenotype
17553787 GOA
involved in cellular senescence IMP
IMP: Inferred from mutant phenotype
15149599 GOA
involved in import into nucleus IMP
IMP: Inferred from mutant phenotype
12417334 GOA
involved in mitotic G2 DNA damage checkpoint signaling IMP
IMP: Inferred from mutant phenotype
23213251 GOA
involved in negative regulation of DNA biosynthetic process IMP
IMP: Inferred from mutant phenotype
11595739 GOA
acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle IGI
IGI: Inferred from genetic interaction
21628527 GOA
involved in negative regulation of cell growth IDA
IDA: Inferred from direct assay
10208428 GOA
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
10208428 GOA
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17553787 GOA
involved in negative regulation of cyclin-dependent protein kinase activity IMP
IMP: Inferred from mutant phenotype
8876165 GOA
involved in negative regulation of phosphorylation IDA
IDA: Inferred from direct assay
10208428 GOA
involved in negative regulation of protein binding IMP
IMP: Inferred from mutant phenotype
11595739 GOA
involved in negative regulation of vascular associated smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
25681685 GOA
involved in positive regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
17420273 GOA
acts upstream of or within positive regulation of protein kinase activity IDA
IDA: Inferred from direct assay
22869755 GOA
involved in positive regulation of reactive oxygen species metabolic process IMP
IMP: Inferred from mutant phenotype
20160708 GOA
involved in regulation of G1/S transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
10208428 GOA
involved in regulation of G2/M transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
17553787 GOA
involved in regulation of cell cycle IDA
IDA: Inferred from direct assay
15149599 GOA
involved in regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
26102367 GOA
involved in regulation of cell cycle G1/S phase transition IMP
IMP: Inferred from mutant phenotype
23213251 GOA
Cellular Component GO Annotation Evidence References Source
part of PCNA-p21 complex IDA
IDA: Inferred from direct assay
18794347 GOA
part of PCNA-p21 complex IMP
IMP: Inferred from mutant phenotype
11595739 GOA
part of PCNA-p21 complex IPI
IPI: Inferred from physical interaction
11463845 GOA
part of cyclin-dependent protein kinase holoenzyme complex IDA
IDA: Inferred from direct assay
17420273 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
22869755 GOA
located in nucleoplasm IDA
IDA: Inferred from direct assay
22869755 GOA
located in nucleus IDA
IDA: Inferred from direct assay
11343236 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
22869755 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDKN1A Protein Structure

CDI

CDI: Cyclin-dependent kinase inhibitor (19 - 69)

  • 0
  • 100
  • 164 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase inhibitor 1

  • CDK-interacting protein 1

CDKN1A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CDKN1A P38936 FKBP1A Homo sapiens Q0VDC6 32814053
Intra
CDKN1A P38936 FKBP1A Homo sapiens Q0VDC6 32814053
Intra
CDKN1A P38936 FKBP1A Homo sapiens Q0VDC6 32814053
Intra
CDKN1A P38936 CDK5 Homo sapiens Q00535 33961781
Intra
CDKN1A P38936 CDK5 Homo sapiens Q00535 30833792
Intra
CDKN1A P38936 CDK5 Homo sapiens Q00535
SPR
15890360
Intra
CDKN1A P38936 CDK14 Homo sapiens O94921 33961781
Intra
CDKN1A P38936 CDK14 Homo sapiens O94921 17517622
Intra
CDKN1A P38936 CDK14 Homo sapiens O94921
Y2H
17517622
Intra
CDKN1A P38936 SARS1 Homo sapiens P49591 32814053
Intra
CDKN1A P38936 SARS1 Homo sapiens P49591 32814053
Intra
CDKN1A P38936 SARS1 Homo sapiens P49591 32814053
Intra
CDKN1A P38936 EIF2S3 Homo sapiens P41091 32814053
Intra
CDKN1A P38936 EIF2S3 Homo sapiens P41091 32814053
Intra
CDKN1A P38936 EIF2S3 Homo sapiens P41091 32814053
Intra
CDKN1A P38936 SIPA1 Homo sapiens Q96FS4
Y2H
21988832
Intra
CDKN1A P38936 REL Homo sapiens Q04864-2 32296183
Intra
CDKN1A P38936 REL Homo sapiens Q04864-2 32296183
Intra
CDKN1A P38936 REL Homo sapiens Q04864-2 32296183
Intra
CDKN1A P38936 HOOK2 Homo sapiens Q96ED9-2 32296183
Intra
CDKN1A P38936 HOOK2 Homo sapiens Q96ED9-2 32296183
Intra
CDKN1A P38936 HOOK2 Homo sapiens Q96ED9-2 32296183
Intra
CDKN1A P38936 DMWD Homo sapiens G5E9A7 32814053
Intra
CDKN1A P38936 DMWD Homo sapiens G5E9A7 32814053
Intra
CDKN1A P38936 DMWD Homo sapiens G5E9A7 32814053
Intra
CDKN1A P38936 TFIP11 Homo sapiens Q9UBB9 32296183
Intra
CDKN1A P38936 TFIP11 Homo sapiens Q9UBB9 32296183
Intra
CDKN1A P38936 TFIP11 Homo sapiens Q9UBB9 32296183
Intra
CDKN1A P38936 MTUS2 Homo sapiens Q5JR59-3 32296183
Intra
CDKN1A P38936 MTUS2 Homo sapiens Q5JR59-3 32296183
Intra
CDKN1A P38936 MTUS2 Homo sapiens Q5JR59-3 32296183
Intra
CDKN1A P38936 STAT5B Homo sapiens P51692 32296183
Intra
CDKN1A P38936 STAT5B Homo sapiens P51692 32296183
Intra
CDKN1A P38936 STAT5B Homo sapiens P51692 32296183
Intra
CDKN1A P38936 SHISA6 Homo sapiens Q6ZSJ9 32296183
Intra
CDKN1A P38936 SHISA6 Homo sapiens Q6ZSJ9 32296183
Intra
CDKN1A P38936 SHISA6 Homo sapiens Q6ZSJ9 32296183
Intra
CDKN1A P38936 CDK3 Homo sapiens Q00526 24218572
Intra
CDKN1A P38936 CDK3 Homo sapiens Q00526 32296183
Intra
CDKN1A P38936 KIFC3 Homo sapiens Q9BVG8-5 32296183
Intra
CDKN1A P38936 KIFC3 Homo sapiens Q9BVG8-5 32296183
Intra
CDKN1A P38936 KIFC3 Homo sapiens Q9BVG8-5 32296183
Intra
CDKN1A P38936 SCML2 Homo sapiens Q9UQR0-1 24358021
Intra
CDKN1A P38936 MEOX2 Homo sapiens Q6FHY5 32296183
Intra
CDKN1A P38936 MEOX2 Homo sapiens Q6FHY5 32296183
Intra
CDKN1A P38936 MEOX2 Homo sapiens Q6FHY5 32296183
Intra
CDKN1A P38936 LRP2BP Homo sapiens Q9P2M1 32296183
Intra
CDKN1A P38936 LRP2BP Homo sapiens Q9P2M1 32296183
Intra
CDKN1A P38936 LRP2BP Homo sapiens Q9P2M1 32296183
Intra
CDKN1A P38936 NABP2 Homo sapiens Q9BQ15 21242961
Intra
CDKN1A P38936 NABP2 Homo sapiens Q9BQ15 21242961
Intra
CDKN1A P38936 TRIM54 Homo sapiens Q9BYV2 32296183
Intra
CDKN1A P38936 TRIM54 Homo sapiens Q9BYV2 32296183
Intra
CDKN1A P38936 TRIM54 Homo sapiens Q9BYV2 32296183
Intra
CDKN1A P38936 ERN1 Homo sapiens O75460-2 32814053
Intra
CDKN1A P38936 ERN1 Homo sapiens O75460-2 32814053
Intra
CDKN1A P38936 ERN1 Homo sapiens O75460-2 32814053
Intra
CDKN1A P38936 q9y649_human Homo sapiens Q9Y649 32814053
Intra
CDKN1A P38936 q9y649_human Homo sapiens Q9Y649 32814053
Intra
CDKN1A P38936 q9y649_human Homo sapiens Q9Y649 32814053
Intra
CDKN1A P38936 PRKAR1B Homo sapiens P31321 32296183
Intra
CDKN1A P38936 PRKAR1B Homo sapiens P31321 32296183
Intra
CDKN1A P38936 PRKAR1B Homo sapiens P31321 32296183
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802 33961781
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802 30833792
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802 15232106
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802 9106657
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802 8756624
Intra
CDKN1A P38936 CDK6 Homo sapiens Q00534 15232106
Intra
CDKN1A P38936 SKP1 Homo sapiens P63208 16376880
Intra
CDKN1A P38936 SKP1 Homo sapiens P63208
PLA
25241761
Intra
CDKN1A P38936 FGFR3 Homo sapiens P22607 32814053
Intra
CDKN1A P38936 FGFR3 Homo sapiens P22607 32814053
Intra
CDKN1A P38936 FGFR3 Homo sapiens P22607 32814053
Intra
CDKN1A P38936 GSN Homo sapiens P06396 32814053
Intra
CDKN1A P38936 GSN Homo sapiens P06396 32814053
Intra
CDKN1A P38936 GSN Homo sapiens P06396 32814053
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 25416956
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 33961781
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
SLC
27107012
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 32296183
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 30833792
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 25416956
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 25416956
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 25416956
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 32296183
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 8861913
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 27107012
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 20605778
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 31515488
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 27107012
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 10873631
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 26496610
Intra
CDKN1A P38936 PCNA Homo sapiens P12004 16189514
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Y2H
27107012
Intra
CDKN1A P38936 TRAF1 Homo sapiens Q13077 25416956
Intra
CDKN1A P38936 TRAF1 Homo sapiens Q13077 25416956
Intra
CDKN1A P38936 TP53 Homo sapiens P04637
PLA
25241761
Intra
CDKN1A P38936 TP53 Homo sapiens P04637
Y2H
21900206
Intra
CDKN1A P38936 MKRN1 Homo sapiens Q9UHC7 19536131
Intra
CDKN1A P38936 MKRN1 Homo sapiens Q9UHC7 19536131
Intra
CDKN1A P38936 CDC6 Homo sapiens Q99741 15232106
Intra
CDKN1A P38936 CDC6 Homo sapiens Q99741
PLA
25241761
Intra
CDKN1A P38936 CDC45 Homo sapiens O75419 15232106
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 30833792
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 25416956
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 15232106
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 27107012
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 27107012
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 25416956
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 8756624
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 25416956
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385 33961781
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Y2H
21988832
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 30833792
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 25416956
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 21988832
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 32296183
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 15232106
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
PLA
25241761
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 27107012
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 31515488
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 27107012
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 25416956
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 26496610
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281 25416956
Intra
CDKN1A P38936 CCNB2 Homo sapiens O95067 33961781
Intra
CDKN1A P38936 CCNB2 Homo sapiens O95067 15232106
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020 30833792
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020 33961781
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020
Y2H
9840943
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020 15232106
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020 24358021
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396 29997244
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396 32814053
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396 29997244
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396 15232106
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396 8756624
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941 16765349
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941 15232106
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941 17418410
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941 24218572
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941 24358021
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
SPR
15890360
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941 24358021
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
PLA
25241761
Intra
CDKN1A P38936 CDK1 Homo sapiens P06493 24218572
Intra
CDKN1A P38936 CDK1 Homo sapiens P06493 26496610
Intra
CDKN1A P38936 CDK1 Homo sapiens P06493 33961781
Intra
CDKN1A P38936 CDK1 Homo sapiens P06493 30833792
Intra
CDKN1A P38936 SKP2 Homo sapiens Q13309 33961781
Intra
CDKN1A P38936 SKP2 Homo sapiens Q13309 16376880
Intra
CDKN1A P38936 SKP2 Homo sapiens Q13309 30833792
Intra
CDKN1A P38936 CCNA2 Homo sapiens P20248 30833792
Intra
CDKN1A P38936 CCNA2 Homo sapiens P20248 26496610
Intra
CDKN1A P38936 CCNA2 Homo sapiens P20248 33961781
Intra
CDKN1A P38936 CCNA2 Homo sapiens P20248
SPR
15890360
Intra
CDKN1A P38936 CCNE1 Homo sapiens P24864 16765349
Intra
CDKN1A P38936 CCNE1 Homo sapiens P24864
Y2H
21988832
Intra
CDKN1A P38936 CCNE1 Homo sapiens P24864 33961781
Intra
CDKN1A P38936 CCNE1 Homo sapiens P24864 8756624
Intra
CDKN1A P38936 SPRED1 Homo sapiens Q7Z699
Y2H
21900206
Intra
CDKN1A P38936 SPRED1 Homo sapiens Q7Z699 32814053
Intra
CDKN1A P38936 SPRED1 Homo sapiens Q7Z699 32814053
Intra
CDKN1A P38936 SPRED1 Homo sapiens Q7Z699 32814053
Intra
CDKN1A P38936 GOLGA2 Homo sapiens Q08379 32296183
Intra
CDKN1A P38936 GOLGA2 Homo sapiens Q08379 32296183
Intra
CDKN1A P38936 GOLGA2 Homo sapiens Q08379 32296183
Intra
CDKN1A P38936 INCA1 Homo sapiens Q0VD86 32296183
Intra
CDKN1A P38936 INCA1 Homo sapiens Q0VD86 32296183
Intra
CDKN1A P38936 INCA1 Homo sapiens Q0VD86 32296183
Intra
CDKN1A P38936 USHBP1 Homo sapiens Q8N6Y0 32296183
Intra
CDKN1A P38936 USHBP1 Homo sapiens Q8N6Y0 32296183
Intra
CDKN1A P38936 USHBP1 Homo sapiens Q8N6Y0 32296183
Intra
CDKN1A P38936 LZTS2 Homo sapiens Q9BRK4 32296183
Intra
CDKN1A P38936 LZTS2 Homo sapiens Q9BRK4 32296183
Intra
CDKN1A P38936 LZTS2 Homo sapiens Q9BRK4 32296183
Intra
CDKN1A P38936 TEX11 Homo sapiens Q8IYF3 16189514
Intra
CDKN1A P38936 TEX11 Homo sapiens Q8IYF3 25416956
Intra
CDKN1A P38936 TEX11 Homo sapiens Q8IYF3 25416956
Intra
CDKN1A P38936 FNDC11 Homo sapiens Q9BVV2 32296183
Intra
CDKN1A P38936 FNDC11 Homo sapiens Q9BVV2 32296183
Intra
CDKN1A P38936 FNDC11 Homo sapiens Q9BVV2 32296183
Intra
CDKN1A P38936 IKZF3 Homo sapiens Q9UKT9 25416956
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279 16765349
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279 27107012
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279 27107012
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279 33961781
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279 25416956
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279 32296183
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279 32296183
Intra
CDKN1A P38936 PCNA Homo sapiens Q6FI35 16616141
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323 32296183
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323 25416956
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323 32296183
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323 32296183
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323 25416956
Intra
CDKN1A P38936 KRTAP3-1 Homo sapiens Q9BYR8 32296183
Intra
CDKN1A P38936 KRTAP3-1 Homo sapiens Q9BYR8 32296183
Intra
CDKN1A P38936 KRTAP3-1 Homo sapiens Q9BYR8 32296183
Cross
CDKN1A P38936 P27958-PRO_0000037566 Hepatitis C virus P27958-PRO_0000037566 10873631
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CDKN1A Proteins

Cat. No. Product Name Accession Purity
HY-P700570 CDKN1A Protein, Human (GST) P38936 (S2-P164) ≥ 90%, as determined by reducing SDS-PAGE.

CDKN1A Antibodies

Cat. No. Product Name Application Reactivity
HY-P80773 p21 Antibody (YA254) WB Human, Mouse
HY-P80773A p21 Antibody (YA254)(PBS only) WB Human, Mouse
HY-P80774A p21 Antibody (YA3460) WB, ICC/IF Human, Mouse, Rat
HY-P80774AA p21 Antibody (YA3460)(PBS only) WB, ICC/IF Human, Mouse, Rat
HY-P84291 p21 Antibody (YA3988) IHC-P, FC, ELISA Human
HY-P84291A p21 Antibody (YA3988)(PBS only) IHC-P, FC, ELISA Human
HY-P84292 p21 Antibody (YA3989) ICC/IF, FC, ELISA Human
HY-P84292A p21 Antibody (YA3989)(PBS only) ICC/IF, FC, ELISA Human
HY-P85782 P21 Antibody (YA5474) IHC-P, WB, ICC/IF, ELISA Human, Mouse
HY-P86368 p21 Antibody (YA6060) WB, IHC-P, ICC/IF, IP, ELISA Mouse, Rat
HY-P86562 P21 Antibody (YA6254) WB, IHC-P, ICC/IF, IP, ELISA Human, Rat

Related Diseases

Diseases Alias
Multiple Endocrine Neoplasia, Type I
  • Multiple Endocrine Neoplasia Type 1

  • MEN1

  • Wermer Syndrome

  • Multiple Endocrine Neoplasia 1

  • Multiple Endocrine Neoplasia, Type 1

  • Men I

  • Endocrine Adenomatosis, Multiple

  • Mea I

  • Men Type I

  • Wermer'S Syndrome

  • Men1 Syndrome

  • Multiple Endocrine Adenomatosis

  • Endocrine Adenomatosis Multiple

  • Men 1

  • Familial Multiple Endocrine Neoplasia Type I

  • Neoplasia, Endocrine, Multiple, Type 1

  • Multiple Endocrine Neoplasia

Tongue Carcinoma
  • Tongue Cancer

  • Malignant Neoplasm Of Tongue

  • Tongue Neoplasms

  • Tongue Neoplasm

Hypervitaminosis A
  • Hypervitaminosis A, Susceptibility To

  • Hyperalimentation Of Vitamin A

Papilloma
  • Papillomatosis

Li-Fraumeni Syndrome
  • Sarcoma Family Syndrome Of Li And Fraumeni

  • Sbla Syndrome

  • LFS

  • Li-Fraumeni Familiar Cancer Susceptibility Syndrome

  • Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome

  • Lfs1

  • Li Fraumeni Syndrome

  • Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome

  • Lfl

  • Sbla Syndrome Li-Fraumeni-Like Syndrome

  • Li-Fraumeni Syndrome 1

Thoracic Cancer
  • Thoracic Tumor

  • Thorax Cancer

  • Thorax Neoplasm

  • Tumor Of Thorax

  • Thoracic Neoplasms

Human Papillomavirus Infectious Disease
  • Hpv

  • Papillomavirus Infections

  • Human Papilloma Virus Infection

Cervical Adenocarcinoma
  • Adenocarcinoma Cervix Uteri

  • Adenocarcinoma Of Cervix

  • Adenocarcinoma Of The Uterine Cervix

  • Adenocarcinoma Of The Cervix Uteri

Retinoblastoma
  • RB

  • Trilateral Retinoblastoma

  • RB1

  • Retinoblastoma, Trilateral

  • Neuroblastoma Of Retina

  • Rb - Retinoblastoma

  • Eye Cancer, Retinoblastoma

  • Retinal Cancer

  • Retinal Tumor

  • Glioma, Retinal

  • Non-Hereditary Retinoblastoma

  • Childhood Cancer Retinoblastoma

  • Malignant Neoplasm Of Retina

  • Retinal Neoplasms

Adenocarcinoma
  • Adenocarcinomas

  • Adenoacanthoma Of Unspecified Site

  • Adenocarcinoid Of Unspecified Site

  • Adenocarcinoid Tumour Of Unspecified Site

  • Adenocarcinoma And Carcinoid Combined Of Unspecified Site

  • Adenocarcinoma Nos

Keratoacanthoma
  • Ka - [Keratoacanthoma]

  • Well-Differentiated Squamous Cell Carcinoma

Bladder Cancer
  • Urinary Bladder Cancer

  • Bladder Carcinoma

  • Urinary Bladder Carcinoma

  • Bladder Neoplasm

  • Bladder Tumor

  • Cancer, Bladder

  • Malignant Neoplasm Of Urinary Bladder

  • Carcinoma Of Bladder

  • Bladder Cancer, Somatic

  • Tumor Of The Bladder

  • Carcinoma Of Urinary Bladder

  • Bladder Carcinoma Urinary

  • Cancer Of The Urinary Bladder

  • Cancer, Urinary Bladder

  • Malignant Bladder Neoplasm

  • Malignant Bladder Tumor

  • Neoplasm Of The Bladder

  • Neoplasm Of The Urinary Bladder

  • Tumor Of The Urinary Bladder

  • Urinary Bladder Neoplasm

  • BLC

  • Urothelial Carcinoma Of The Bladder

  • Bladder Tumors

  • Urinary Bladder Neoplasms

  • Bladder Cancer Nos

  • Vesical Cancer Nos

  • Malignant Neoplasm Of Bladder, Part Unspecified

  • Malignant Tumour Of Urinary Bladder

  • Primary Malignant Neoplasm Of Bladder

Colorectal Cancer
  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon

Squamous Cell Carcinoma
  • Epidermoid Carcinoma

  • Squamous Cell Cancer

  • Carcinoma, Squamous Cell

  • Squamous Cell Skin Cancer

  • Malignant Squamous Cell Tumor

  • Squamous Carcinoma

  • Squamous Cell Epithelioma

  • Carcinoma Squamous Cell

  • Neoplasms, Squamous Cell

  • Squamous Cell Carcinoma - Category

  • Malignant Squamous Cell Neoplasm

  • Squamous Cell Carcinoma Of Skin

Ataxia-Telangiectasia
  • Ataxia Telangiectasia

  • Louis-Bar Syndrome

  • AT

  • At1

  • Ataxia-Telangiectasia Syndrome

  • Ataxia - Telangiectasia Variant

  • Boder-Sedgwick Syndrome

  • Louis Bar Syndrome

  • Cerebello-Oculocutaneous Telangiectasia

  • Immunodeficiency With Ataxia Telangiectasia

  • A-T

  • Ataxia Telangiectasia Syndrome

  • Atm

  • Telangiectasia, Cerebello-Oculocutaneous

  • Ataxia-Telangiectasia Variant

Endometrial Cancer
  • Endometrial Carcinoma

  • Endometrial Neoplasm

  • Malignant Neoplasm Of Endometrium

  • Endometrioid Carcinoma

  • Endometrial Neoplasms

  • Carcinoma, Endometrioid

  • Endometrial Cancer, Familial

  • Endometrial Carcinoma, Somatic

  • Endometrial Cancer, Susceptibility To

  • Endometrial Ca

  • Malignant Endometrial Neoplasm

  • Neoplasm Of Endometrium

  • Primary Malignant Neoplasm Of Endometrium

  • Tumor Of Endometrium

  • Carcinoma Of The Endometrium

  • Endometrioid Carcinoma Of Female Reproductive System

  • ENDMC

  • Carcinoma Endometrioid

  • Endometrial Cancers

  • Cancer, Endometrial

  • Uterine Corpus Cancer

Polyploidy
  • Polyploid

  • Polyploidy Syndrome

Malignant Pleural Mesothelioma
  • Malignant Mesothelioma Of Pleura

  • Pleural Malignant Mesothelioma

Pancreatic Adenocarcinoma
  • Adenocarcinoma Of The Pancreas

  • Adenocarcinoma Of Pancreas

  • Pancreas Adenocarcinoma

  • Malignant Exocrine Neoplasm

  • Primary Pancreatic Adenocarcinoma

  • Adenocarcinoma Of Islet Cell Of Pancreas

  • Islet Cell Adenocarcinoma Of Unspecified Site

  • Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site

Lung Cancer
  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma

Transitional Cell Carcinoma
  • Transitional Cell Neoplasm

  • Carcinoma, Transitional Cell

  • Transitional Carcinoma

  • Transitional Cell Tumor

  • Urothelial Cell Carcinoma

  • Carcinoma Transitional Cell

  • Transitional Cell Carcinoma Of Bladder

Ovarian Cancer
  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary

Breast Cancer
  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation

Bladder Urothelial Carcinoma
  • Bladder Transitional Cell Carcinoma

  • Transitional Cell Carcinoma Of Bladder

  • Transitional Cell Carcinoma Of The Bladder

  • Urinary Bladder Urothelial Carcinoma

  • Urothelial Bladder Carcinoma

  • Carcinoma Transitional Cell Bladder

  • Tcc - [Transitional Cell Carcinoma] Of Bladder

Breast Ductal Carcinoma
  • Ductal Breast Carcinoma

  • Duct Carcinoma

  • Carcinoma, Ductal

  • Mammary Ductal Carcinoma

  • Ductal Carcinoma

Glioblastoma
  • Glioblastoma Multiforme

  • Gbm

  • Adult Glioblastoma Multiforme

  • Grade Iv Adult Astrocytic Tumor

  • Primary Glioblastoma Multiforme

  • Spongioblastoma Multiforme

  • Adult Glioblastoma

  • Primary Glioblastoma

Melanoma
  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas

Colon Adenocarcinoma
  • Adenocarcinoma Of Colon

  • Adenocarcinoma Of The Colon

  • Colonic Adenocarcinoma

Pancreatic Cancer
  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Focal Segmental Glomerulosclerosis
  • Familial Idiopathic Steroid-Resistant Nephrotic Syndrome

  • Focal Glomerulosclerosis

  • Fsgs

  • Segmental Glomerulosclerosis

  • Glomerulosclerosis, Focal Segmental

  • Fgs

  • Focal Glomerular Sclerosis

  • Familial Idiopathic Nephrotic Syndrome

  • Focal Sclerosis With Hyalinosis

  • Glomerulosclerosis, Focal

  • Glomerulosclerosis Focal

  • Glomerulosclerosis, Segmental, Focal

  • Focal Segmental Glomerulosclerosis, Not Otherwise Specified

Fibrosarcoma
  • Neoplasms, Fibrous Tissue

  • Fibrocytic Tumor

  • Fibrosarcoma Of Soft Tissue

  • Fibrous Tissue Neoplasm

Cystadenocarcinoma
Coronary Restenosis
Thyroid Gland Anaplastic Carcinoma
  • Anaplastic Thyroid Carcinoma

  • Anaplastic Thyroid Cancer

  • Thyroid Cancer, Anaplastic

  • Thyroid Carcinoma, Anaplastic

  • Thyroid Carcinoma Anaplastic

Laryngeal Squamous Cell Carcinoma
  • Epidermoid Carcinoma Of The Larynx

  • Squamous Cell Carcinoma Of Larynx

  • Squamous Cell Carcinoma Of The Larynx

  • Squamous Cell Carcinoma Of Head And Neck

Acute Promyelocytic Leukemia
  • Leukemia, Acute Promyelocytic

  • Acute Myeloblastic Leukemia Type 3

  • Aml M3

  • APL

  • Leukemia, Acute Promyelocytic, Somatic

  • Aml With T(15

  • 17)(Q22

  • Q12)

  • (Pml/Raralpha) And Variants

  • Apml

  • Acute Myeloblastic Leukemia 3

  • Acute Myeloid Leukemia With T(15

  • 17)(Q22

  • Q12)

  • (Pml/Raralpha) And Variants

  • Acute Myeloblastic Leukaemia Type 3

  • Acute Myeloid Leukaemia M3

  • Acute Myeloid Leukemia M3

  • Acute Promyelocytic Leukaemia

  • M3 Anll

  • Myeloid Leukemia, Acute, M3

  • Leukemia Promyelocytic Acute

  • Leukemia, Promyelocytic, Acute

  • Leukemia, Acute, Promyelocytic

Rectum Cancer
  • Malignant Neoplasm Of Rectum

  • Rectal Cancer

  • Cancer Of Rectum

  • Carcinoma Of Rectum

  • Carcinoma Of The Rectum

  • Malignant Rectal Tumor

  • Malignant Rectum Tumor

  • Malignant Tumor Of Rectum

  • Rectal Carcinoma

  • Rectal Cancers

  • Cancer, Rectal

Ureteral Obstruction
Lymphoblastic Lymphoma
  • Lymphoma, Lymphoblastic

  • Lymphoma Lymphoblastic

  • Precursor Cell Lymphoblastic Lymphoma

  • Precursor Cell Lymphoblastic Leukemia Lymphoma

Prostate Cancer
  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer

Cervical Cancer
  • Cervical Cancer, Somatic

  • Neoplasm Of Uterine Cervix

  • Cervix Cancer

  • Uterine Cervical Neoplasm

  • Cervical Neoplasm

  • Cervix Uteri Cancer

  • Tumor Of The Cervix Uteri

  • CERCA

  • Uterine Cervical Cancer

  • Neoplasms Cervical

  • Uterine Cervical Neoplasms

  • Cervical Cancers

  • Cancer, Cervical, Somatic

  • Malignant Tumor Of Cervix

  • Cervix Carcinoma

Hepatocellular Carcinoma
  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour

Kaposi Sarcoma
  • Kaposi'S Sarcoma

  • Kaposi Sarcoma, Susceptibility To

  • Kaposi'S Sarcoma Of Lung

  • Kaposi'S Sarcoma Of Palate

  • Kaposi'S Sarcoma Of Soft Tissue

  • Kaposi'S Sarcoma-Associated Herpesvirus

  • Multiple Idiopathic Pigmented Hemangiosarcoma

  • Multiple Idiopathic Pigmented Hemangiosarcoma, Susceptibility To

  • African Lymphadenopathic Kaposi'S Sarcoma

  • Anal Kaposi'S Sarcoma

  • Cardiac Kaposi'S Sarcoma

  • Central Nervous System Kaposi'S Sarcoma

  • Conjunctival Kaposi'S Sarcoma

  • Corneal Kaposi'S Sarcoma

  • Cutaneous Kaposi'S Sarcoma

  • Esophageal Kaposi'S Sarcoma

  • Gallbladder Kaposi'S Sarcoma

  • Gastric Kaposi'S Sarcoma

  • Intestinal Kaposi'S Sarcoma

  • Kaposi'S Sarcoma Of Anus

  • Kaposi'S Sarcoma Of Central Nervous System

  • Kaposi'S Sarcoma Of Conjunctiva

  • Kaposi'S Sarcoma Of Cornea

  • Kaposi'S Sarcoma Of Esophagus

  • Kaposi'S Sarcoma Of Gastrointestinal Sites

  • Kaposi'S Sarcoma Of Heart

  • Kaposi'S Sarcoma Of Lymph Nodes

  • Kaposi'S Sarcoma Of Penis

  • Kaposi'S Sarcoma Of Skin

  • Kaposi'S Sarcoma Of Soft Tissues

  • Kaposi'S Sarcoma Of The Cns

  • Kaposi'S Sarcoma Of The Gallbladder

  • Kaposi'S Sarcoma Of The Prostate

  • Kaposi'S Sarcoma, Lung

  • Kaposi'S Sarcoma, Skin

  • Lymph Node Kaposi'S Sarcoma

  • Lymphadenopathic Kaposi'S Sarcoma

  • Palate Kaposi'S Sarcoma

  • Penis Kaposi'S Sarcoma

  • Prostate Kaposi'S Sarcoma

  • Pulmonary Kaposi'S Sarcoma

  • Soft Tissue Kaposi'S Sarcoma

  • Hhv8

  • Human Herpesvirus 8

  • Kshv

  • Kaposi Sarcoma Herpesvirus

  • Mediterranean Kaposi Sarcoma

  • Non Aids Related Kaposi Sarcoma

  • Sarcoma, Kaposi

  • Sarcoma, Kaposi, Susceptibility To

  • Non-Aids-Related Kaposi Sarcoma

  • Angiolymphoid Hyperplasia

  • Angiofollicular Ganglionic Hyperplasia

  • Multi-Centric Castleman'S Disease

Suppressor Of Tumorigenicity 3
  • Cervical Carcinoma

  • ST3

  • Tumor-Suppressor Gene, Hela Cell Type

  • Tshl

  • Cervical Carcinoma, Tumor-Suppressor Gene Involved In

  • Ccts

  • Cervix Carcinoma

Gastric Cancer
  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach

Barrett Esophagus
  • Barrett'S Esophagus

  • Barrett Esophagus/Esophageal Adenocarcinoma

  • Barrett Metaplasia

  • Barrett'S Ulcer Of Esophagus

  • Ulcerative Esophagitis

  • Barrett'S Esophagus With Esophagitis

  • Barrett'S Oesophagus

  • Barretts Syndrome

  • Barrett Syndrome

  • BE

  • Peptic Ulcer Of Esophagus

  • Adenocarcinoma Of Esophagus

Plasmacytoma
  • Solitary Plasmacytoma

  • Solitary Myeloma

  • Myeloma - Solitary

  • Myeloma, Solitary

  • Plasmacytoma - Category

  • Solitary Osseous Plasmacytoma

  • Solitary Plasmacytoma Without Mention Of Remission

  • Localised Malignant Plasma Cell Tumour Nos

  • Plasmacytoma Nos

Esophageal Cancer
  • Esophageal Carcinoma

  • Carcinoma Of Esophagus

  • Esophageal Squamous Cell Carcinoma, Somatic

  • Esophageal Carcinoma, Somatic

  • Esophagus Cancer

  • Gastric Cardia Adenocarcinoma

  • Esophageal Neoplasms

  • Esophageal Cancer, Somatic

  • Cancer Of Esophagus

  • Cancer Of Oesophagus

  • Carcinoma Of Oesophagus

  • Ca Lower Third Oesophagus

  • Ca Middle Third Oesophagus

  • Malignant Neoplasm Of Distal Third Of Esophagus

  • Malignant Neoplasm Of Lower Third Of Oesophagus

  • Malignant Neoplasm Of Middle Third Of Oesophagus

  • Malignant Neoplasm Of Proximal Third Of Esophagus

  • Malignant Neoplasm Of Upper Third Esophagus

  • Malignant Tumor Of Abdominal Esophagus

  • Malignant Tumor Of Distal Third Of Esophagus

  • Malignant Tumor Of Proximal Third Of Esophagus

  • Malignant Tumor Of The Middle Third Of The Esophagus

  • ESCR

  • Aerodigestive Tract Cancer

  • Escc

  • Esophageal Squamous Cell Carcinoma

  • Cancer, Esophageal

  • Malignant Neoplasm Of Esophagus

  • Squamous Cell Carcinoma Of Esophagus

  • Malignant Neoplasm Of Middle Third Of Esophagus

Skin Melanoma
  • Cutaneous Melanoma

  • Malignant Ear Melanoma

  • Malignant Lip Melanoma

  • Malignant Lower Limb Melanoma

  • Malignant Melanoma Of Ear And/Or External Auricular Canal

  • Malignant Melanoma Of Skin Of Lower Limb

  • Malignant Melanoma Of Skin Of Trunk Except Scrotum

  • Malignant Melanoma Of Skin Of Upper Limb

  • Malignant Neck Melanoma

  • Malignant Scalp Melanoma

  • Malignant Trunk Melanoma

  • Malignant Upper Limb Melanoma

  • Melanoma, Cutaneous Malignant

  • Melanoma

  • Malignant Melanoma Of Skin

  • Melanoma Nos

  • Malignant Mole, Meaning Melanoma Of Unspecified Site

  • Melanoma Of Unspecified Site

  • Cutaneous Malignant Melanoma

  • Mm - [Malignant Melanoma]

Cheilitis
Burkitt Lymphoma
  • Burkitt'S Lymphoma

  • BL

  • Burkitt Lymphoma, Somatic

  • Burkitt Lymphoma/Leukaemia

  • Burkitt'S Tumor

  • Burkitt'S Tumor Or Lymphoma

  • Malignant Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma

  • Burkitt Tumor

  • Burkitts Lymphoma

  • Lymphoma, Small Noncleaved-Cell

  • Burkitt Tumour

  • Diffuse Small Noncleaved Malignant Burkitt Lymphoma

  • Malignant Burkitt Lymphoma

  • “Burkitt-Like” Lymphoma

  • Undifferentiated Burkitt Lymphoma

  • Small Noncleaved Cell Burkitt Lymphoma

B-Cell Lymphoma
  • Lymphoma, B-Cell

  • B-Cell Lymphomas

  • B-Cell Lymphocytic Neoplasm

  • Lymphoma B-Cell

  • B-Cell Lymphoma Nos

Arthritis
  • Inflammatory Joint Disease

  • Inflammatory Disorder Of Joint

Prolactinoma
  • Prolactin-Producing Pituitary Gland Adenoma

  • Prolactin-Secreting Pituitary Adenoma

  • Forbes-Albright Syndrome

  • Lactotroph Adenoma

  • Prl-Secreting Pituitary Adenoma

  • Prloma

  • Pituitary Lactotrophic Adenoma

  • Familial Prolactinoma

  • Pituitary Adenoma, Prolactin-Secreting

  • Prolactinoma Of Pituitary Gland

  • PSPA

Shigellosis
  • Dysentery, Bacillary

  • Bacillary Dysentery

  • Shigella Boydii Infectious Disease

  • Shigella Flexneri Infectious Disease

  • Shigella Gastroenteritis

  • Shigella Sonnei Infectious Disease

  • Shigella Infections

Cockayne Syndrome
  • Cockayne'S Syndrome

  • Dwarfism-Retinal Atrophy-Deafness Syndrome

  • Neill-Dingwall Syndrome

  • Progeria-Like Syndrome

  • Progeroid Nanism

  • Cs

Basal Cell Carcinoma
  • Basal Cell Cancer

  • Basal Cell Neoplasm

  • Basal Cell Carcinoma Of Skin

  • Malignant Basal Cell Tumor

  • Basal Cell Tumor

  • Epithelioma Basal Cell

  • Malignant Basal Cell Neoplasm

  • Rodent Ulcer

  • Carcinoma Basal Cell

  • Neoplasms, Basal Cell

  • Basal Cell Carcinomas

  • Experimental Organism Basal Cell Carcinoma

  • Nodulo-Ulcerative Basal Cell Carcinoma

  • Basalioma

  • Basal Cell Epithelioma Of Skin

  • Bcc - [Basal Cell Carcinoma] Of Skin

  • Rodent Ulcer Of Skin

  • Rodent Ulcer Of Unspecified Site

  • Basal Cell Epithelioma Of Unspecified Site

Retinal Cancer
  • Malignant Neoplasm Of Retina

  • Retinal Neoplasms

  • Malignant Retinal Neoplasm

  • Malignant Tumor Of Retina

  • Neoplasm Of Retina

  • Retinal Tumor

  • Retinal Neoplasm

  • Cancer Of The Retina

  • Malignant Retinal Tumour

  • Malignant Tumour Of Retina

  • Primary Malignant Neoplasm Of Retina

Hepatoblastoma
Leukodystrophy, Hypomyelinating, 8, With Or Without Oligodontia And/Or Hypogonadotropic Hypogonadism
  • Hypomyelinating Leukodystrophy 8 With Or Without Oligodontia And-Or Hypogonadotropic Hypogonadism

  • HLD8

  • Cerebellar Hypoplasia With Endosteal Sclerosis

  • 4h Leukodystrophy 2

  • Endosteal Sclerosis-Cerebellar Hypoplasia Syndrome

  • Leukodystrophy, Hypomyelinating, Type 8, With/Without Oligodontia And/Or Hypogonadotropic Hypogonadism

Brain Cancer
  • Adult Brain Tumor

  • Malignant Neoplasm Of Brain

  • Brain Neoplasms

  • Brain Neoplasm

  • Neoplasm Of Brain

  • Primary Malignant Neoplasm Of Brain

  • Brain Tumors

  • Adult Malignant Brain Neoplasm

  • Brain Neoplasm, Adult

  • Bt - Brain Tumour

  • Malignant Brain Tumour

  • Malignant Primary Brain Neoplasm

  • Malignant Primary Brain Tumor

  • Malignant Tumor Of Adult Brain

  • Malignant Tumor Of Brain

  • Primary Brain Neoplasm

  • Primary Brain Tumor

  • Tumor Of The Brain

  • Brain Tumor, Adult

  • Brain Tumor Primary

  • Malignant Primary Brain Tumors

  • Primary Brain Tumors

  • Cancer, Brain

  • Brain Tumor, Primary

Rhabdomyosarcoma
Cervical Squamous Cell Carcinoma
  • Squamous Cell Carcinoma Of The Cervix Uteri

  • Squamous Cell Carcinoma Of Cervix

Osteogenic Sarcoma
  • Osteosarcoma

  • OSRC

  • Osteosarcoma, Somatic

  • Neoplasms, Bone Tissue

  • Bone Tissue Neoplasm

  • Osteoid Sarcoma

  • Skeletal Sarcoma

  • Osteosarcoma Of Bone

  • Bone Sarcoma

High Grade Glioma
  • Malignant Glioma

  • Glial Cell Tumor

  • Glioma, Malignant

  • Malignant Neuroglial Tumor

  • Neuroglial Tumor

  • Glioma

  • Malignant Gliomas

Leukemia, Chronic Myeloid
  • Chronic Myeloid Leukemia

  • Chronic Myelogenous Leukemia

  • CML

  • Chronic Granulocytic Leukemia

  • Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib

  • Chronic Myeloid Leukaemia

  • Chronic Granulocytic Leukaemia

  • Chronic Myelogenous Leukaemia

  • Myeloid Leukemia, Chronic

  • Leukemia, Chronic Myelogenous

  • Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic

  • Cml - Chronic Myelogenous Leukemia

  • Cgl

  • Chronic Myelocytic Leukemia

  • Leukemia, Chronic Myeloid, Atypical

  • ACML

  • Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative

  • Myeloid Leukemia Chronic

  • Leukemia, Myeloid, Chronic

  • Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative

  • Cml- [Chronic Myeloid Leukaemia]

  • Cgl - [Chronic Granulocytic Leukaemia]

  • Chronic Myelocytic Leukaemia

Lung Cancer Susceptibility 3
  • Lung Adenocarcinoma

  • Adenocarcinoma Of Lung

  • LNCR3

  • Adenocarcinoma Of Lung, Susceptibility To

  • Bronchogenic Lung Adenocarcinoma

  • Nonsmall Cell Adenocarcinoma

  • Adenocarcinoma Lung

  • Lung Adenocarcinomas

  • Non-Small Cell Adenocarcinoma

Medulloblastoma
  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site

Ocular Cancer
  • Eye Neoplasm

  • Eye Carcinoma

  • Eye Cancer

  • Eye Neoplasms

  • Malignant Eye Neoplasm

  • Neoplasm Of Eye

  • Neoplasm Of Eye Proper

  • Ocular Tumor

  • Carcinoma Of Eye

  • Ocular Carcinoma

  • Malignant Tumor Of Eye

Neuroblastoma
  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma

Skin Papilloma
  • Cutaneous Papilloma

  • Papilloma Of Skin

  • Papilloma Skin

Squamous Cell Carcinoma, Head And Neck
  • Squamous Cell Carcinoma Of The Head And Neck

  • HNSCC

  • Head And Neck Squamous Cell Carcinoma

  • Squamous Cell Carcinoma Of Lip

  • Squamous Cell Carcinoma, Head And Neck, Somatic

  • Carcinoma Of The Head And Neck

  • Squamous Cell Carcinomas Of Head And Neck

  • Scchn

  • Squamous Cell Carcinoma Of The Hypopharynx

  • Squamous Cell Carcinoma Of The Oropharynx

  • Squamous Cell Carcinoma Of Salivary Glands

  • Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses

  • Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses

  • Squamous Cell Carcinoma Of The Oral Cavity

  • Squamous Cell Carcinoma Of The Lip

  • Carcinoma, Squamous Cell Of Head And Neck

  • Lip Squamous Cell Carcinoma

  • Carcinoma, Squamous Cell, Head And Neck

  • Salivary Gland Squamous Cell Carcinoma

  • Cancer Of Head And Neck

  • Squamous Cell Carcinoma Of Oropharynx Nos

Pheochromocytoma
  • Pheochromocytoma, Susceptibility To

  • Phaeochromocytoma

  • Adrenal Gland Chromaffin Paraganglioma

  • Adrenal Gland Chromaffinoma

  • Adrenal Gland Paraganglioma

  • Adrenal Gland Pheochromocytoma

  • Chromaffin Paraganglioma Of The Adrenal Gland

  • Intraadrenal Paraganglioma

  • PCC

  • Chromaffin Cell Tumor

  • Medullary Chromaffinoma

  • Medullary Paraganglioma

  • Pheochromoblastoma

  • Pheochromocytomas

  • Chromaffin Cell Neoplasm

  • Pheochromocytoma, Malignant

Lung Adenoma
  • Adenoma Of Lung

  • Pulmonary Adenoma

Muscular Dystrophy
  • Muscular Dystrophies

  • Congenital Md

  • Congenital Muscular Dystrophy

  • Cmd

  • Mdc

  • Dystrophy, Muscular

  • Gower'S Muscular Dystrophy

  • Progressive Musclular Dystrophy

  • Pseudohypertrophic Atrophy

  • Pseudohypertrophic Muscle Paralysis

  • Pseudohypertrophic Muscular Atrophy

  • Pseudohypertrophic Muscular Dystrophy

  • Pseudohypertrophic Paralysis

  • Pseudomuscular Hypertrophy

Thrombocytopenia
  • Low Platelet Count

  • Low Platelets

  • Decreased Platelets

  • Platelet Dysfunction Nos

Retinal Disease
  • Retinal Diseases

  • Retinal Disorder

  • Retinal Disorders

Myeloma, Multiple
  • Multiple Myeloma

  • Plasma Cell Myeloma

  • Kahler Disease

  • Myelomatosis

  • Medullary Plasmacytoma

  • Multiple Myeloma, Resistance To

  • Myeloma

  • Plasma Cell Dyscrasia

  • Kahler'S Disease

  • Multiple Myeloma, Susceptibility To

  • Myeloma - Multiple

  • Kahler-Bozzolo Disease

  • Plasma Cell Myelomas

  • MM

  • Plasma Cell Neoplasm

  • Primary Systemic Amyloidosis

  • Primary Amyloidosis

  • Immunoglobulin Deposition Disease

  • Plasmacytic Myeloma

  • Multiple Myelomata

  • Multiple Myeloma Nos

  • Multiple Myeloma Without Mention Of Remission

  • Monostotic Plasma Cell Myeloma

  • Mm - [Multiple Myeloma]

Melanoma, Cutaneous Malignant 1
  • Familial Melanoma

  • Melanoma, Cutaneous Malignant, Susceptibility To, 1

  • Melanoma, Malignant

  • CMM1

  • Melanoma, Cutaneous Malignant

  • Cmm

  • Familial Atypical Mole-Malignant Melanoma Syndrome

  • Fammm

  • Melanoma, Familial

  • Mlm

  • Dysplastic Nevus Syndrome, Hereditary

  • Dns

  • B-K Mole Syndrome

  • Melanoma, Cutaneous Malignant, 1

  • Malignant Melanoma, Cutaneous

  • Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

  • Dysplastic Nevus Syndrome

  • Cutaneous Melanoma

  • Familial Atypical Mole Melanoma Syndrome

  • Hereditary Melanoma

Fanconi Anemia, Complementation Group A
  • Fanconi Anemia

  • Fanconi Pancytopenia

  • Fanconi Anemia Complementation Group A

  • FANCA

  • Fa

  • Fanconi Panmyelopathy

  • Fanconi'S Anemia

  • Fanconi Anaemia

  • Fanconi'S Anaemia

  • Fanconi Hypoplastic Anemia

  • Estren-Dameshek Variant Of Fanconi Anemia

  • Estren-Dameshek Variant Of Fanconi Pancytopenia

  • Fanconi Anemia Estren-Dameshek Variant

  • Fanconis Anemia

Colonic Benign Neoplasm
  • Colon Neoplasm

  • Colonic Mass

  • Colonic Tumor

  • Neoplasm Of Colon

  • Neoplasm Of The Colon

  • Colonic Neoplasms

  • Colon Cancer

  • Colon Carcinoma Nos

  • Colonic Cancer

  • Metastatic Colon Cancer Nos

Breast Adenocarcinoma
  • Mammary Adenocarcinoma

  • Adenocarcinoma Of Breast

Eye Disease
  • Eye Diseases

  • Abnormality Of The Eye

  • Toxoplasma Oculopathy

Leukemia, Acute Myeloid
  • Acute Myeloid Leukemia

  • Leukemia, Acute Myelogenous

  • Acute Myelogenous Leukemia

  • AML

  • Leukemia, Acute Myeloid, Susceptibility To

  • Acute Myeloblastic Leukemia

  • Leukemia, Acute Myeloid, Reduced Survival In, Somatic

  • Acute Myeloid Leukaemia

  • Leukemia, Myelocytic, Acute

  • Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

  • Secondary Aml

  • Acute Myelocytic Leukemia

  • Acute Myeloid Leukemia, Somatic

  • Leukemia, Acute Myeloid, Somatic

  • Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

  • Acute Myeloblastic Leukaemia

  • Acute Myelogenous Leukaemia

  • Aml - Acute Myeloid Leukemia

  • Acute Myeloid Leukemia With Cebpa Somatic Mutations

  • Aml With Cebpa Somatic Mutations

  • Inherited Acute Myeloid Leukemia

  • Familial Aml

  • Inherited Aml

  • Pure Familial Aml

  • Pure Familial Acute Myeloid Leukemia

  • Secondary Acute Myeloid Leukemia

  • Therapy-Related Aml And Myelodysplastic Syndrome

  • Acute Myeloid Leukemia, Secondary

  • Acute Non-Lymphoblastic Leukemia

  • Acute Non-Lymphocytic Leukemia

  • Acute Biphenotypic Leukemia

  • Acute Undifferentiated Leukemia

  • Acute Myeloblastic Leukaemia With Multilineage Dysplasia

  • Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

  • Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Nervous System Disease
  • Abnormality Of The Nervous System

  • Nervous System Diseases

  • Nervous System Disorder

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus CDKN1A VGNC VGNC:60713
Mus musculus CDKN1A MGD MGI:104556
Bos taurus CDKN1A VGNC VGNC:27142
Canis familiaris CDKN1A VGNC VGNC:39068
Rattus norvegicus CDKN1A RGD RGD:69328
Macaca mulatta CDKN1A VGNC VGNC:70988
Others CDKN1A NCBI