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79025

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11

Inhibitors & Agonists

8

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-113654
    AMG 7905

    		TRP Channel Others
    AMG 7905 is a hypothermia-inducing transient receptor potential vanilloid type 1 (TRPV1) antagonist. AMG 7905 potentiates TRPV1 channels activation by protons and drives the reflectory inhibition of thermogenesis and tail-skin vasoconstriction, while potently blocking channel activation by capsaicin .
    AMG 7905
  • HY-113654A
    AMG 7905 TFA

    		TRP Channel Cardiovascular Disease
    AMG 7905 TFA is a hypothermia-inducing transient receptor potential vanilloid type 1 (TRPV1) antagonist. AMG 7905 TFA potentiates TRPV1 channels activation by protons and drives the reflectory inhibition of thermogenesis and tail-skin vasoconstriction, while potently blocking channel activation by capsaicin .
    AMG 7905 TFA
  • HY-155117
    MRS7925

    		5-HT Receptor Inflammation/Immunology
    MRS7925 (Compound 43) is a 5-HT2BR antagonist (Ki: 17 nM). MRS7925 can be used for research of fibrosis .
    MRS7925
  • HY-R03787
    mmu-miR-7025-3p mimic

    		MicroRNA Cancer
    mmu-miR-7025-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-7025-3p mimic
    mmu-miR-7025-3p mimic
  • HY-RI03787A
    mmu-miR-7025-3p antagomir

    		MicroRNA Cancer
    mmu-miR-7025-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-7025-3p antagomir
    mmu-miR-7025-3p antagomir
  • HY-RI03788
    mmu-miR-7025-5p inhibitor

    		MicroRNA Cancer
    mmu-miR-7025-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-7025-5p inhibitor
    mmu-miR-7025-5p inhibitor
  • HY-R03788A
    mmu-miR-7025-5p agomir

    		MicroRNA Cancer
    mmu-miR-7025-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-7025-5p agomir
    mmu-miR-7025-5p agomir
  • HY-R03787A
    mmu-miR-7025-3p agomir

    		MicroRNA Cancer
    mmu-miR-7025-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-7025-3p agomir
    mmu-miR-7025-3p agomir
  • HY-R03788
    mmu-miR-7025-5p mimic

    		MicroRNA Cancer
    mmu-miR-7025-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-7025-5p mimic
    mmu-miR-7025-5p mimic
  • HY-RI03788A
    mmu-miR-7025-5p antagomir

    		MicroRNA Cancer
    mmu-miR-7025-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-7025-5p antagomir
    mmu-miR-7025-5p antagomir
  • HY-RI03787
    mmu-miR-7025-3p inhibitor

    		MicroRNA Cancer
    mmu-miR-7025-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-7025-3p inhibitor
    mmu-miR-7025-3p inhibitor

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