MIS18A - MIS18 kinetochore protein A Gene
Also Known as B28; FASP1; C21orf45; C21orf46; MIS18alpha; hMis18alpha
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 54069
Summary
Enables identical protein binding activity. Predicted to be involved in CENP-A containing chromatin assembly. Predicted to act upstream of or within chromosome segregation; obsolete pericentric heterochromatin organization; and protein localization to chromosome, centromeric region. Predicted to be located in nucleoplasm. Predicted to be part of CENP-A recruiting complex. Predicted to be active in chromatin; chromosome, centromeric region; and nucleus. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in testis (RPKM 8.3), bone marrow (RPKM 3.6) and 24 other tissues.
MIS18A Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_018944.3 | NP_061817.1 | protein Mis18-alpha |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables identical protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
17043677 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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MIS18A Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Références |
|---|---|---|---|---|---|---|---|
|
Intra
|
MIS18A | Q9NYP9 | MBIP | Homo sapiens | Q9NS73-5 | 25416956 | |
|
Intra
|
MIS18A | Q9NYP9 | MBIP | Homo sapiens | Q9NS73-5 | 25416956 | |
|
Intra
|
MIS18A | Q9NYP9 | BRD8 | Homo sapiens | Q9H0E9-2 | 25416956 | |
|
Intra
|
MIS18A | Q9NYP9 | KIF1B | Homo sapiens | O60333-2 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | KIF1B | Homo sapiens | O60333-2 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | KIF1B | Homo sapiens | O60333-2 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 25416956 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 21516116 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 17199038 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 17199038 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 25036634 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 25036634 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 31515488 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 25416956 | |
|
Intra
|
MIS18A | Q9NYP9 | OIP5 | Homo sapiens | O43482 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | PPP1R13B | Homo sapiens | Q96KQ4 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | PPP1R13B | Homo sapiens | Q96KQ4 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | CNGA3 | Homo sapiens | Q16281 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | CNGA3 | Homo sapiens | Q16281 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | b4dj69_human | Homo sapiens | B4DJ69 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | b4dj69_human | Homo sapiens | B4DJ69 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | CCDC115 | Homo sapiens | Q96NT0 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | CCDC115 | Homo sapiens | Q96NT0 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | NUP58 | Homo sapiens | Q9BVL2 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | NUP58 | Homo sapiens | Q9BVL2 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | NUP58 | Homo sapiens | Q9BVL2 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | TXLNA | Homo sapiens | P40222 | 33961781 | |
|
Intra
|
MIS18A | Q9NYP9 | TXLNA | Homo sapiens | P40222 | 28514442 | |
|
Intra
|
MIS18A | Q9NYP9 | DMAP1 | Homo sapiens | Q9NPF5 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | DMAP1 | Homo sapiens | Q9NPF5 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | ZNF655 | Homo sapiens | Q8N720 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | ZNF655 | Homo sapiens | Q8N720 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | STX11 | Homo sapiens | O75558 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | WFS1 | Homo sapiens | O76024 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | WFS1 | Homo sapiens | O76024 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | WFS1 | Homo sapiens | O76024 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | ABI3 | Homo sapiens | Q9P2A4 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | AIMP2 | Homo sapiens | Q13155 | 25416956 | |
|
Intra
|
MIS18A | Q9NYP9 | AIMP2 | Homo sapiens | Q13155 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | AIMP2 | Homo sapiens | Q13155 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | GLYCTK | Homo sapiens | Q8IVS8 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | PRPS1 | Homo sapiens | P60891 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | PRPS1 | Homo sapiens | P60891 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | PRPS1 | Homo sapiens | P60891 | 32814053 | |
|
Intra
|
MIS18A | Q9NYP9 | IFT20 | Homo sapiens | Q8IY31-3 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | IFT20 | Homo sapiens | Q8IY31-3 | 32296183 | |
|
Intra
|
MIS18A | Q9NYP9 | NDEL1 | Homo sapiens | Q9GZM8 | 17043677 |
Cross: Cross-species interaction
Intra: Intraspecies interaction