2. Apoptosis Metabolic Enzyme/Protease
  3. Apoptosis Endogenous Metabolite
  4. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol  (Synonyms: 9,11-Dehydroergosterol peroxide; 9(11)-DHEP)

Cat. No.: HY-N7175
Handling Instructions Technical Support

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis.

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5,8-Epidioxyergosta-6,9(11),22-trien-3-ol

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol 화학구조

CAS No. : 86363-50-0

사이즈 가격 재고 수량
1 mg 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
5 mg 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
10 mg   견적 받기  
50 mg   견적 받기  
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5,8-Epidioxyergosta-6,9(11),22-trien-3-ol Related Antibodies

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제품 설명

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis[1][2].

IC50 & Target[1]

Microbial Metabolite

 

Cellular Effect
Cell Line Type Value Description References
A549 IC50
10.37 6
Compound: 6
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
[PMID: 23511021]
A549 IC50
10.37 6
Compound: 6
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
[PMID: 23511021]
Hep 3B2 IC50
15.52 6
Compound: 6
Cytotoxicity against human Hep3B cells
Cytotoxicity against human Hep3B cells
[PMID: 23511021]
Hep 3B2 IC50
15.52 6
Compound: 6
Cytotoxicity against human Hep3B cells
Cytotoxicity against human Hep3B cells
[PMID: 23511021]
HepG2 IC50
7.73 6
Compound: 6
Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
[PMID: 23511021]
HepG2 IC50
7.73 6
Compound: 6
Cytotoxicity against human HepG2 cells
Cytotoxicity against human HepG2 cells
[PMID: 23511021]
MCF7 IC50
9.18 6
Compound: 6
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
[PMID: 23511021]
MCF7 IC50
9.18 6
Compound: 6
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
[PMID: 23511021]
MDA-MB-231 IC50
7.32 6
Compound: 6
Cytotoxicity against human MDA-MB-231 cells
Cytotoxicity against human MDA-MB-231 cells
[PMID: 23511021]
MDA-MB-231 IC50
7.32 6
Compound: 6
Cytotoxicity against human MDA-MB-231 cells
Cytotoxicity against human MDA-MB-231 cells
[PMID: 23511021]
In Vitro

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide) is an effective inhibitor of HL60 leukemia cell growth and apoptosis-inducer[1].
Apoptosis induced by 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol from Ganoderma Lucidum mycelium in human malignant melanoma cells is Mcl?1 dependent[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol Related Antibodies
분자량

426.63

화학식

C28H42O3
CAS No.
SMILES

C[C@@]1(CC[C@@H]2O)C([C@]3(C=C[C@]1(C2)OO3)[C@]4([H])CC[C@]5([H])[C@H](C)/C=C/[C@H](C)C(C)C)=CC[C@@]45C
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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5,8-Epidioxyergosta-6,9(11),22-trien-3-ol Related Classifications

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The dilution calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5,8-Epidioxyergosta-6,9(11),22-trien-3-ol86363-50-09,11-Dehydroergosterol peroxide9(11)-DHEPApoptosisEndogenous MetaboliteHL60 leukemia cell growthmalignant melanoma cellsMcl 1Inhibitorinhibitorinhibit

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상품명:
5,8-Epidioxyergosta-6,9(11),22-trien-3-ol
Cat. No.:
HY-N7175
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