Gfra2 - GDNF family receptor alpha 2 Gene

Also Known as Retl2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25136

Summary

Enables glial cell-derived neurotrophic factor receptor activity. Involved in negative regulation of protein autophosphorylation. Predicted to be anchored component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Biomarker of Parkinsonism. Orthologous to human GFRA2 (GDNF family receptor alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Gfra2 Products (1)

mRNA Protein Name
NM_012750.2 NP_036882.1 GDNF family receptor alpha-2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables glial cell-derived neurotrophic factor receptor activity IDA
IDA: Inferred from direct assay
9608533 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of protein autophosphorylation IDA
IDA: Inferred from direct assay
9608533 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GDNF family receptor alpha-2

  • glial cell line derived neurotrophic factor family receptor alpha 2

  • tyrosine kinase receptor ligand 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS27452 Gfra2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05387 GFRA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20935 Gfra2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gfra2 NCBI NCBI:2675
Mus musculus Gfra2 NCBI NCBI:14586