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Cat. No.: HY-169238

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17β-HSD7-IN-1

17β-HSD7-IN-1 (compound 4) is an inhibitor of 17β-HSD7, with inhibitory effect agasint the formation of Estradiol (IC₅₀=63 nM)..

For research use only. We do not sell to patients.

Formula: C₂₉H₄₈N₂O₃
Molecular Weight:472.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

17β-HSD7-IN-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

17β-HSD7-IN-1 (compound 4) is an inhibitor of 17β-HSD7, with inhibitory effect agasint the formation of Estradiol (IC₅₀=63 nM).^[1].

All 17β-HSD Isoforms :

17β-HSD5/AKR1C3

Chemical Information

Molecular Weight 472.70
Formula C₂₉H₄₈N₂O₃
SMILES

[H][C@@]12CC[C@@]3([C@]1(CC[C@]4([C@]2(CC[C@]5(NC(CC[C@]45C)=O)[H])[H])[H])C)CN(C(O3)=O)CCCCCCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sancéau JY, et al. Synthesis and characterization of targeted 17β-hydroxysteroid dehydrogenase type 7 inhibitors. J Steroid Biochem Mol Biol. 2024 Sep;242:106544. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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17β-HSD7-IN-1

All 17β-HSD Isoforms