42-O-(2-Azidoethyl)-Rapamycin

製品番号: HY-180123 純度: 97.20%: Data Sheet SDS COA 取扱説明書
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42-O-(2-Azidoethyl)-Rapamycin (Compound 4) is an azide compound that can be used as a drug intermediate to synthesize the derivative of Rapamycin (HY-10219).

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42-O-(2-Azidoethyl)-Rapamycin 構造式

CAS 番号 : 159351-89-0

容量	価格（税別）	在庫状況	数量
5 mg	$1000	在庫あり	Estimated Time of Arrival: December 31
10 mg	$1500	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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生物活性
純度とドキュメンテーション
参考文献
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製品説明

42-O-(2-Azidoethyl)-Rapamycin (Compound 4) is an azide compound that can be used as a drug intermediate to synthesize the derivative of Rapamycin (HY-10219)^[1].

分子量

983.24

分子式

C₅₃H₈₂N₄O₁₃

CAS 番号

159351-89-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(C(N1[C@@](C(O[C@@](CC([C@@H](/C=C(C)\[C@@H](O)[C@H](C([C@@H](C[C@@H](/C=C\C=C\C=C2C)C)C)=O)OC)C)=O)([C@@H](C[C@@H]3CC[C@@H](OCCN=[N+]=[N-])[C@H](OC)C3)C)[H])=O)([H])CCCC1)=O)[C@]4(O)O[C@@](C[C@@H]/2OC)([H])CC[C@H]4C

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (101.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0170 mL	5.0852 mL	10.1705 mL
5 mM	0.2034 mL	1.0170 mL	2.0341 mL
10 mM	0.1017 mL	0.5085 mL	1.0170 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 97.20%

Select Batch:

データシート (271 KB) SDS (252 KB)

COA (253 KB) HNMR (434 KB) RP-HPLC (223 KB) MS (68 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Ying JY, et al. A kind of rapamycin derivative and its preparation method and application. CN115160343.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0170 mL	5.0852 mL	10.1705 mL	25.4261 mL
	5 mM	0.2034 mL	1.0170 mL	2.0341 mL	5.0852 mL
	10 mM	0.1017 mL	0.5085 mL	1.0170 mL	2.5426 mL
	15 mM	0.0678 mL	0.3390 mL	0.6780 mL	1.6951 mL
	20 mM	0.0509 mL	0.2543 mL	0.5085 mL	1.2713 mL
	25 mM	0.0407 mL	0.2034 mL	0.4068 mL	1.0170 mL
	30 mM	0.0339 mL	0.1695 mL	0.3390 mL	0.8475 mL
	40 mM	0.0254 mL	0.1271 mL	0.2543 mL	0.6357 mL
	50 mM	0.0203 mL	0.1017 mL	0.2034 mL	0.5085 mL
	60 mM	0.0170 mL	0.0848 mL	0.1695 mL	0.4238 mL
	80 mM	0.0127 mL	0.0636 mL	0.1271 mL	0.3178 mL
	100 mM	0.0102 mL	0.0509 mL	0.1017 mL	0.2543 mL