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  4. 5,5'-Methylenebis(2-hydroxybenzoic acid)

5,5'-Methylenebis(2-hydroxybenzoic acid)  (Synonyms: 5,5'-Methylenedisalicylic acid)

Cat. No.: HY-W345226
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5,5'-Methylenebis(2-hydroxybenzoic acid) (5,5'-Methylenedisalicylic acid) is a metal-organic framework (MOF).

For research use only. We do not sell to patients.

5,5'-Methylenebis(2-hydroxybenzoic acid)

5,5'-Methylenebis(2-hydroxybenzoic acid) Chemical Structure

CAS No. : 122-25-8

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5,5'-Methylenebis(2-hydroxybenzoic acid) Related Antibodies

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Description

5,5'-Methylenebis(2-hydroxybenzoic acid) (5,5'-Methylenedisalicylic acid) is a metal-organic framework (MOF).

Cellular Effect
Cell Line Type Value Description References
A549 CC50
>100 μM
Compound: 8, NSC-14778
Cytotoxicity against human A549 cells after 48 hrs
Cytotoxicity against human A549 cells after 48 hrs
[PMID: 20108931]
A549 CC50
100 μM
Compound: 8, NSC-14778
Cytotoxicity against human A549 cells after 48 hrs
Cytotoxicity against human A549 cells after 48 hrs
[PMID: 20108931]
A549 EC50
>100 μM
Compound: 8, NSC-14778
Antiviral activity against Dengue virus type 2 infected in human A549 cells assessed as decrease in viral E protein production by cell-based flavivirus immunodetection assay
Antiviral activity against Dengue virus type 2 infected in human A549 cells assessed as decrease in viral E protein production by cell-based flavivirus immunodetection assay
[PMID: 20108931]
CCRF-CEM IC50
>276 μg/mL
Compound: 21
Inhibitory concentration for cytopathicity of HIV-1 (HTLV-IIIB) in CEM cells
Inhibitory concentration for cytopathicity of HIV-1 (HTLV-IIIB) in CEM cells
[PMID: 1704066]
MT4 CC50
>100 μg/mL
Compound: 21
50% cytotoxic concentrations for mock-infected MT-4 cells.
50% cytotoxic concentrations for mock-infected MT-4 cells.
[PMID: 1704066]
MT4 IC50
>100 μg/mL
Compound: 21
Inhibitory concentration for cytopathicity of HIV-1 (HTLV-IIIB) in MT-4 cells
Inhibitory concentration for cytopathicity of HIV-1 (HTLV-IIIB) in MT-4 cells
[PMID: 1704066]
Molecular Weight

288.26

Formula

C15H12O6
CAS No.
SMILES

O=C(O)C1=CC(=CC=C1O)CC2=CC=C(O)C(=C2)C(=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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5,5'-Methylenebis(2-hydroxybenzoic acid) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5,5'-Methylenebis(2-hydroxybenzoic acid)122-25-85,5'-Methylenedisalicylic acidMOFsMetal-Organic FrameworksInhibitorinhibitorinhibit

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