country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N17452

Copy Link Print Information

6’-O-Caffeoyl-(6S,9R)-roseoside

6’-O-Caffeoyl-(6S,9R)-roseoside is a caffeoyl glucoside derivative. 6’-O-Caffeoyl-(6S,9R)-roseoside inhibits the production of NO and PGE₂.

For research use only. We do not sell to patients.

CAS No.: 1827325-67-6
Formula: C₂₈H₃₆O₁₁
Molecular Weight:548.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

6’-O-Caffeoyl-(6S,9R)-roseoside Chemical Structure

CAS No.: 1827325-67-6

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

6’-O-Caffeoyl-(6S,9R)-roseoside is a caffeoyl glucoside derivative. 6’-O-Caffeoyl-(6S,9R)-roseoside inhibits the production of NO and PGE₂^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	50 μM Compound: 1	Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production incubated for 1 hr followed by stimulation with LPS for 24 hrs by enzyme immuno assay Inhibition of NF-kappaB/AP-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production incubated for 1 hr followed by stimulation with LPS for 24 hrs by enzyme immuno assay	[PMID: 27590705]

In Vitro

6’-O-Caffeoyl-(6S,9R)-roseoside (Compound 1) (25 h) can inhibit LPS-induced NO and PGE₂ production in RAW 264.7 macrophages, and the IC₅₀ values of both mediators are greater than 50 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1827325-67-6
Molecular Weight 548.58
Formula C₂₈H₃₆O₁₁
SMILES

OC(C=C1/C=C/C(OC[C@H]([C@H]([C@@H]([C@H]2O)O)O)O[C@H]2O[C@H](C)/C=C/[C@@]3(C(C)(CC(C=C3C)=O)C)O)=O)=C(C=C1)O
Structure Classification
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Seo S, et al. 6'-O-Caffeoyldihydrosyringin isolated from Aster glehni suppresses lipopolysaccharide-induced iNOS, COX-2, TNF-α, IL-1β and IL-6 expression via NF-κB and AP-1 inactivation in RAW 264.7 macrophages. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4592-4598. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote