1. PI3K/Akt/mTOR
  2. PI3K

GDC-0077 

Cat. No.: HY-101562 Purity: 99.07% ee.: 100.00%
Handling Instructions

GDC-0077 is an orally available PI3K inhibitor with potential antineoplastic activity. GDC-0077 is extracted from patent WO 2017001645 A1, formula I.

For research use only. We do not sell to patients.

GDC-0077 Chemical Structure

GDC-0077 Chemical Structure

CAS No. : 2060571-02-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 484 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
1 mg USD 180 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
5 mg USD 540 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 900 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
25 mg USD 1800 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 2880 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg USD 4680 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

GDC-0077 is an orally available PI3K inhibitor with potential antineoplastic activity. GDC-0077 is extracted from patent WO 2017001645 A1, formula I.

IC50 & Target[1]

PI3K

 

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 180 mg/mL (441.86 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4548 mL 12.2739 mL 24.5477 mL
5 mM 0.4910 mL 2.4548 mL 4.9095 mL
10 mM 0.2455 mL 1.2274 mL 2.4548 mL
*Please refer to the solubility information to select the appropriate solvent.
References
References
Molecular Weight

407.37

Formula

C₁₈H₁₉F₂N₅O₄

CAS No.

2060571-02-8

SMILES

C[[email protected]@H](C(N)=O)NC1=CC=C(C2=NC(N3[[email protected]](C(F)F)COC3=O)=CN2CCO4)C4=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.07% ee.: 100.00%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
GDC-0077
Cat. No.:
HY-101562
Quantity:

GDC-0077

Cat. No.: HY-101562