Bisbenzylisoquinoline Alkaloids
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Bisbenzylisoquinoline Alkaloids (3)
- Formula: C38H42N2O7
- Molecular Weight: 638.75
Tetrandrine 2'-N-α-oxide (compound 13) is a bisbenzylisoquinoline alkaloid anti-inflammatory agent that can be isolated from the roots of Stephania tetrandra. Tetrandrine 2'-N-α-oxide may be used in research related to inflammatory diseases.
- Formula: C22H23NO4
- Molecular Weight: 365.42
Tylophorinidine is a natural phenanthroindolizidine alkaloid present in Tylophora ovata, and exhibits NFκB inhibitory activity. Tylophorinidine suppresses the cell viability of 3D co-culture spheroids derived from triple-negative breast cancer cells. Tylophorinidine is used in related research on triple-negative breast cancer.
- Formula: C37H38N2O8
- Molecular Weight: 638.71
S-Secoantioquine (Secantioquine) is a bisbenzylisoquinoline alkaloid secoderivative. In the rat striate membrane experiment, S-Secoantioquine shows weak displacement activity on 3H-SCH 23390 binding site, and certain displacement activity on 3H-raclopride binding site.
