2. Natural Products
  3. Plants
  4. Polygonaceae
  5. Polygonum aviculare L.

Polygonum aviculare L.

Polygonum aviculare L. (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N10481
    Aviculin 156765-33-2
    Aviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC50 of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio.
    Aviculin