GnRH Receptor Inhibitor
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Quinestrol
0 ImagesQuinestrol (W-3566) is an orally effective synthetic estrogen compound that acts on CYP3A4, CYP1A2, and GnRH. Quinestrol interferes with GnRH release and disrupts the hypothalamic-pituitary-ovarian axis. Quinestrol downregulates the gene expression of follicle-stimulating hormone β and luteinizing hormone β, induces oxidative stress, damages reproductive organs, reduces sperm density and motility, increases sperm malformation rate, and alters the levels of sex hormones such as testosterone, luteinizing hormone, estradiol, and progesterone. Quinestrol can be used in studies related to reproductive function regulation.
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LUF5771
0 ImagesLUF5771 is a potent allosteric recombinant luteinizing hormone (recLH) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy.
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Dimethandrolone undecanoate
0 ImagesCat. No.: HY-164032CAS No.: 366472-45-9Synonyms: 7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoateDimethandrolone undecanoate (7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate) exhibits withrogens and progesterone activity. Dimethandrolone undecanoate inhibits production of gonadotropins, suppresses testosterone production, and thus inhibits sperm production. Dimethandrolone undecanoate is potent for development of male hormone contraceptives.
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Antide acetate
0 ImagesCat. No.: HY-P0013ACAS No.: 625092-10-6Synonyms: D-21074 acetate; ORF 23541 acetateAntide (D-21074) acetate is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer.
