Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11051)
Related Products (11051)
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Naloxegol-13C,d2
0 ImagesCat. No.: HY-A0118S1Synonyms: NKTR-118-13C,d2; AZ-13337019-13C,d2Naloxegol-13C,d2 (NKTR-118-13C,d2) is 13C labeled Naloxegol. Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.
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Alvelestat-13C,d3
0 ImagesCat. No.: HY-15651SSynonyms: AZD9668-13C,d3Alvelestat-13C,d3 (AZD9668-13C,d3) is the deuterated, 13C-labeled Alvelestat (HY-15651). Alvelestat (AZD9668) is an orally active, selective inhibitor of neutrophil elastase. Alvelestat reduces elastase activity, myeloperoxidase release, neutrophil recruitment and activation, and calcium phosphate precipitation; promotes smooth muscle cell colonization and collagen deposition; and inhibits the formation of neutrophil extracellular traps (NETs) as well as NET-derived neutrophil elastase activity. Alvelestat restores endothelial dysfunction, regulates antioxidant factors, improves the expression of endothelial tight junctions, reduces vascular leakage, and accelerates wound healing. Alvelestat prevents pulmonary hemorrhage, matrix protein degradation, airspace enlargement, and small airway wall remodeling; and alleviates cigarette-induced inflammatory responses. Alvelestat inhibits the growth of abdominal aortic aneurysms exacerbated by Porphyromonas gingivalis. Alvelestat can be used in research related to chronic obstructive pulmonary disease, abdominal aortic aneurysm, radiation-induced skin injury, and bronchiectasis.
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Salbutamon-d9 hydrochloride
0 ImagesCat. No.: HY-132453SCAS No.: 1346605-08-0Salbutamon-d9 hydrochloride is the deuterium labeled Salbutamon hydrochloride.
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Liothyronine-d3
0 ImagesCat. No.: HY-A0070AS3Synonyms: Triiodothyronine-d3; 3,3',5-Triiodo-L-thyronine-d3; T3-d3Liothyronine-d3 is deuterated labeled Liothyronine (HY-A0070A). Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
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6-Heptyltetrahydro-2H-pyran-2-one-d2
0 ImagesCat. No.: HY-W009815SCAS No.: 1082581-84-7Synonyms: δ-Laurolactone-d26-Heptyltetrahydro-2H-pyran-2-one-d2 is deuterated labeled 6-Heptyltetrahydro-2H-pyran-2-one.
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Clenpenterol-d5 hydrochloride
0 ImagesCat. No.: HY-135566SCAS No.: 1794793-20-6Clenpenterol-d5 (hydrochloride) is deuterium labeled Clenpenterol (hydrochloride).
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2,3,3′,4,5,5′-Hexachloro biphenyl-13C12
0 ImagesCat. No.: HY-W718614S2,3,3′,4,5,5′-Hexachloro biphenyl-13C12 is 13C labeled 2,3,3',4,5,5'-Hexachloro-1,1'-biphenyl.
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Estradiol-d2-1
0 ImagesCat. No.: HY-B0141S6CAS No.: 3188-46-3Synonyms: β-Estradiol-d2-1; E2-d2-1; 17β-Estradiol-d2-1; 17β-Oestradiol-d2-1Estradiol-d2-1 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
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Flucytosine-15N2 (hydrochloride)
0 ImagesCat. No.: HY-B0139AS1Synonyms: 5-Fluorocytosine-15N2 hydrochloride; NSC 103805-15N2 hydrochloride; Ro 2-9915-15N2 hydrochlorideFlucytosine-15N2 (5-Fluorocytosine-15N2) hydrochloride is the 15N-labeled Flucytosine hydrochloride (HY-B0139). Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells.
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(Leu-13C6,15N)-Ile-OH TFA
0 ImagesCat. No.: HY-W101298SSynonyms: L-Leucyl-13C6,15N-L-isoleucine TFA(Leu-13C6,15N)-Ile-OH (L-Leucyl-13C6,15N-L-isoleucine) TFA is the deuterium labeled Leu-Ile-OH. Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) synthesis.
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1,2-Bis(methylthio)benzene-d6
0 ImagesCat. No.: HY-W796728SCAS No.: 3067019-39-71,2-Bis(methylthio)benzene-d6 is the deuterium labeled 1,2-Bis(methylthio)benzene (HY-W654023).
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Tetrasul-d4
0 ImagesCat. No.: HY-124901SCAS No.: 2732862-67-6Tetrasul-d4 is the deuterium labeled Tetrasul.
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(±)-Lisofylline-d6
0 ImagesCat. No.: HY-126042SCAS No.: 1185995-26-9(±)-Lisofylline-d6 is the deuterium labeled (±)-Lisofylline.
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Bestatin-d10
0 ImagesCat. No.: HY-B0134S1Synonyms: Ubenimex-d10Bestatin-d10 (Ubenimex-d10) is deuterium labeled Bestatin. Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects.
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Sarafloxacin-d8
0 ImagesCat. No.: HY-B0343SCAS No.: 1352879-52-7Synonyms: A-56620-d8Sarafloxacin-d8 (A-56620-d8) is the d8 labeled Sarafloxacin (HY-B0343). Sarafloxacin (A-56620) is a fluoroquinolone Antibacterial agent. Sarafloxacin inhibits the growth of Staphylococcus aureus, Enterobacteriaceae, and both aminoglycoside-sensitive and aminoglycoside-resistant strains of Pseudomonas aeruginosa.
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Nirmatrelvir-d6
0 ImagesCat. No.: HY-138687S1CAS No.: 2861202-75-5Synonyms: PF-07321332-d6Nirmatrelvir-d6 (PF-07321332-d6) is deuterium labeled Nirmatrelvir. Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CLPRO) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research.
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Cinnamyl Alcohol-d5
0 ImagesCat. No.: HY-Y0078SCAS No.: 1044940-87-5
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Bilastine-d4
0 ImagesCat. No.: HY-14447S1CAS No.: 2747918-37-0Bilastine-d4 is deuterium labeled Bilastine. Bilastine is an oral histamine H1-receptor antagonist. Bilastine can be used for allergic rhinitis and urticaria studies, and it also improves diabetic nephropathy in mice, showing safety for the central nervous system.
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Ethyl linoleate-d5
0 ImagesCat. No.: HY-W013812S1CAS No.: 1169764-57-1Synonyms: Linoleic Acid ethyl ester-d5; Ethyl linoleate, pure-d5; Mandenol-d5Ethyl linoleate-d5 (Linoleic Acid ethyl ester-d5) is deuterium labeled Ethyl linoleate. Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators.
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