Cinnamyl Alcohol-d5
Cinnamyl Alcohol-d5 is deuterated labeled Cinnamyl Alcohole (HY-Y0045). Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, exhibits anti-obesity, antioxidant and anti-inflammatory activities.
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- CAS No.: 1044940-87-5
- Formule: C9H5D5O
- Masse moléculaire:139.21
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1044940-87-5
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Masse moléculaire 139.21
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Formule C9H5D5O
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SMILES
OC/C=C/C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Hwang DI, et al. Cinnamyl Alcohol, the Bioactive Component of Chestnut Flower Absolute, Inhibits Adipocyte Differentiation in 3T3-L1 Cells by Downregulating Adipogenic Transcription Factors. Am J Chin Med. 2017;45(4):833-846. [Content Brief]
[2]. Choi YR, et al., Cinnamyl Alcohol Attenuates Adipogenesis in 3T3-L1 Cells by Arresting the Cell Cycle. Int J Mol Sci. 2024 Jan 5;25(2):693. [Content Brief]
[3]. Kang YH, et al., Cinnamyl alcohol attenuates vasoconstriction by activation of K⁺ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase. Exp Mol Med. 2012 Dec 31;44(12):749-55. [Content Brief]
[5]. Zou L, et al., The anti-inflammatory effects of cinnamyl alcohol on sepsis-induced mice via the NLRP3 inflammasome pathway. Ann Transl Med. 2022 Jan;10(2):48. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cinnamyl Alcohol-d5 Related Classifications
HY-Y0078S Related Classifications
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Keywords
- Cinnamyl Alcohol-d5
- 1044940-87-5
- Isotope-Labeled Compounds
- Potassium Channel
- NO Synthase
- ERK
- ROCK
- AMPK
- Akt
- PPAR
- KcsA
- Nitric oxide synthases
- NOS
- Extracellular signal regulated kinases
- Rho-associated protein kinase
- Rho-associated kinase
- Rho-kinase
- ROK
- AMP-activated protein kinase
- PKB
- Protein kinase B
- Peroxisome proliferator-activated receptors
- Inhibitor
- inhibitor
- inhibit