Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1263)
Related Products (1263)
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VL-422 derivative
0 ImagesCat. No.: HY-186305CAS No.: 3078747-38-0VL-422 derivative is an ionizable lipid component of targeted lipid nanoparticles. VL-422 derivative formulated with a helper lipid, cholesterol, and a PEGylated lipid forms lipid nanoparticles (LNPs). VL-422 derivative can be used for in vivo or ex vivo delivery of agents to immune cells.
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DSPE-PEG2000-A7R
0 ImagesCat. No.: HY-172272ADSPE-PEG2000-A7R is a PEG compound which composed of DSPE and a tumor vascular targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, which is overexpressed in various tumors.
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DSG-PEG5000-Biotin
0 ImagesCat. No.: HY-183170CDSG-PEG5000-Biotin is a conjugate composed of DSG, PEG chains, and biotin. DSG-PEG5000-Biotin combines the membrane compatibility of phospholipids with the high affinity of biotin for avidin/streptavidin, enabling applications such as targeted drug delivery systems and nanoparticle modification.
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PtdIns-(3)-P1(1,2-dioctanoyl) sodium
0 ImagesCat. No.: HY-131482CAS No.: 299216-98-1PtdIns-(3)-P1(1,2-dioctanoyl) sodium (compound 1b) is a glycogen phosphate that plays a key role in eukaryotic membrane trafficking and agonist-activated intracellular signaling.
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DSPC-d13
0 ImagesSynonyms: 1,2-Distearoyl-sn-glycero-3-PC-d13; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13DSPC-d13 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
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DSPE-PEG5000-LTLRWVGLMS
0 ImagesCat. No.: HY-172486DSPE-PEG5000-LTLRWVGLMS is a PEG compound which composed of DSPE and a decapeptide (LTLRWVGLMS). The chondroitin sulfate proteoglygan NG2 is a receptor for LTLRWVGLMS. LLRWVGLMS shows the homing of pericytes associated with tumor blood vessels. DSPE-PEG5000-LTLRWVGLMS can be used for drug delivery.
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DSPE-PEG10000-Mannose
0 ImagesCat. No.: HY-168374DCAS No.: 1829524-73-3DSPE-PEG10000-Mannose is a conjugate composed of DSPE, a PEG chain, and terminal mannose. DSPE-PEG10000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.
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DSPC-d79
0 ImagesSynonyms: 1,2-Distearoyl-sn-glycero-3-PC-d79; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79DSPC-d79 (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
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DPPE-PEG2000-N3
0 ImagesCat. No.: HY-W1052051Synonyms: DPPE-PEG2000-AzideDPPE-PEG2000-N3 (DPPE-PEG2000-Azide) is a conjugate composed of DPPE, PEG chains, and terminal azido groups (-N3). DPPE-PEG2000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.
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DOPE-PEG3400-NHS
0 ImagesCat. No.: HY-203300BDOPE-PEG3400-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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DSPE-PEG3400-GRGDS
0 ImagesCat. No.: HY-172684ADSPE-PEG3400-GRGDS is a PEG compound which composed of DSPE and an anti-adhesion peptide (GRGDS). GRGDS can block the binding and adhesion of extracellular matrix to cell surface integrins. DSPE-PEG3400-GRGDS can be used for drug delivery.
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Lipid I97
0 ImagesCat. No.: HY-171898CAS No.: 3046404-81-0Lipid I97 is an ionizable lipid derived from vitamin B5 (pKa = 6.23). Lipid I97 can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vivo. Lipid I97 can be studied in research for enhancing mRNA transfection efficiency and long-term stability as well as formulation of mRNA vaccines.
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DSG-PEG10000-Galactose
0 ImagesCat. No.: HY-183174DDSG-PEG10000-Galactose is a conjugate composed of DSG, a PEG chain, and terminal galactose. DSG-PEG10000-Galactose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of galactose, making it suitable for research in biomaterial construction and drug delivery.
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1,2-Dioctanoyl-sn-glycero-3-phosphocholine
0 Images1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
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C12 DG PEG (MW 2000)
0 ImagesCat. No.: HY-173376Synonyms: 1,2-Didodecanoyl-rac-glycero-3-methoxypolyethylene glycol (MW 2000)C12 DG PEG (1,2-Didodecanoyl-rac-glycero-3-methoxypolyethylene glycol) (MW 2000) is a PEG lipid that can be used in lipid nanoparticle and liposome formation. C12 DG PEG (MW 2000) is promising for research of cancers.
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DSPE-PEG3400-EB1
0 ImagesCat. No.: HY-172726ADSPE-PEG3400-EB1 is a PEG compound which composed of DSPE and pH responsive membrane-penetrating peptide (EB1). DSPE-PEG3400-EB1 can be used for drug delivery.
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PBA-Q76-O16B
0 ImagesCat. No.: HY-185778CAS No.: 3027931-27-4PBA-Q76-O16B is a lipid that cannot cross the blood-brain barrier on its own, but can mediate cargo delivery into the brains of mice when blended with NT1 lipids. After forming stable small-sized lipid nanoparticles with NT1-O12B, PBA-Q76-O16B delivers drugs into the brains of mice. When formulated into lipid nanoparticles with NT1-O14B, PBA-Q76-O16B delivers (-27) GFP-Cre recombinase into mouse brain cells, driving functional gene recombination in multiple brain regions. PBA-Q76-O16B can be used in studies related to lipid nanoparticles (LNPs).
