Hydroxycarboxylic Acid Receptor (HCAR) Inhibitor
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Hydroxycarboxylic Acid Receptor (HCAR) Inhibitor (1)
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GPR81 agonist 1
0 ImagesGPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC50s of 58 nM and 50 nM for human and mouse GPR81, respectively. GPR81 agonist 1 inhibits lipolysis in differentiated 3T3-L1 adipocytes. GPR81 agonist 1 suppresses lipolysis in mice without cutaneous flushing. GPR81 agonist 1 displays remarkable selectivity for GPR81 over GPR109a.
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August 31
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August 31
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