1620992-67-7
Chemical Structure
GPR81 agonist 1
- CAS No.: 1620992-67-7
- Formula:C22H30N4O2S2
- Molecular Weight:446.63
IUPAC Name: (1r,4r)-4-methyl-N-(5-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)-4-(thiophen-2-yl)thiazol-2-yl)cyclohexane-1-carboxamide
InChIKey: ZLQAEANISSHOLB-WKILWMFISA-N
SMILES: O=C([C@H]1CC[C@H](C)CC1)NC2=NC(C3=CC=CS3)=C(CC(N4CCN(C)CC4)=O)S2
Biological Activity: GPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC50s of 58 nM and 50 nM for human and mouse GPR81, respectively. GPR81 agonist 1 inhibits lipolysis in differentiated 3T3-L1 adipocytes. GPR81 agonist 1 suppresses lipolysis in mice without cutaneous flushing. GPR81 agonist 1 displays remarkable selectivity for GPR81 over GPR109a[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GPR81 agonist 1 | 99.73% | GPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC50s of 58 nM and 50 nM for human and mouse GPR81, respectively. GPR81 agonist 1 inhibits lipolysis in differentiated 3T3-L1 adipocytes. GPR81 agonist 1 suppresses lipolysis in mice without cutaneous flushing. GPR81 agonist 1 displays remarkable selectivity for GPR81 over GPR109a. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
