Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
All Product Categories
-
Isotope-Labeled Compounds Related Products (11051)
Related Products (11051)
-
Paroxetine-d4
0 ImagesCat. No.: HY-122272SCAS No.: 923932-45-0Synonyms: BRL29060-d4Paroxetine-d4 (BRL29060-d4) is the deuterated-labeled Paroxetine (HY-122272). Paroxetine (BRL29060) is an orally active and selective serotonin reuptake inhibitor (SSRI) and apoptosis inducer with blood-brain barrier permeability. Paroxetine inhibits nitric oxide synthase and CYP2D6, induces desensitization of 5-HT1A/1B/1D autoreceptors, downregulates 5-HT2 receptors, and promotes the production of inflammatory cytokines. Paroxetine is a weak norepinephrine (NE) uptake inhibitor and possesses antitumor activity. Paroxetine is widely used in research concerning depression, obsessive-compulsive disorder, panic disorder, social phobia, generalized anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, hot flashes, and related conditions.
-
Liraglutide-d8 tetraTFA
0 ImagesCat. No.: HY-P0014ASLiraglutide-d8 tetraTFA is deuterium labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the study of type 2 diabetes mellitus.
-
Pyridoxine-13C4
0 ImagesCat. No.: HY-B1328S3Synonyms: Pyridoxol-13C4Pyridoxine-13C4 (Pyridoxol-13C4) is 13C labeled Pyridoxine. Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
-
Tetrahydrozoline-d4 hydrochloride
0 ImagesSynonyms: Tetryzoline-d4 hydrochlorideTetrahydrozoline-d4 (hydrochloride) is the deuterium labeled Tetrahydrozoline hydrochloride. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion.
-
3-Mercapto-1-octanol-d5
0 ImagesCat. No.: HY-156482SCAS No.: 3028869-14-6Synonyms: 1-Octan-7,7,8,8,8-d5-ol, 3-mercapto-3-Mercapto-1-octanol-d5 is deuterated labeled 3-Mercapto-1-octanol.
-
5-Androsten-3-β-ol-17-one-d6
0 ImagesCat. No.: HY-154769S5-Androsten-3-β-ol-17-one-d6 is deuterated labeled 5-Androsten-3-β-ol-17-one.
-
Imatinib-d8 mesylate
0 ImagesCat. No.: HY-132386SCAS No.: 1092942-83-0Synonyms: STI571-d8 mesylate; CGP-57148B-d8 mesylateImatinib-d8 (mesylate) is the deuterium labeled Imatinib mesylate.
-
Vismodegib-d7
0 ImagesCat. No.: HY-W716916CAS No.: 2733145-73-6Vismodegib-d7 is deuterium labeled Vismodegib. Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively.
-
Bexarotene-13C6
0 ImagesCat. No.: HY-14171S2Synonyms: LGD1069-13C6Bexarotene-13C6 (LGD1069-13C6) is 13C labeled Bexarotene. Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 >10000 nM). Bexarotene can be used for the research of cutaneous T-cell lymphoma.
-
Epiallopregnanolone-d5
0 ImagesCat. No.: HY-124463S1Synonyms: 5α,3β-THDOC-d5Epiallopregnanolone-d5 (5α,3β-THDOC-d5) is deuterium labeled Epiallopregnanolone. Epiallopregnanolone (5α,3β-THDOC), a 3β-hydroxy neurosteroid, an antagonist at GABAA receptors and a NMDA receptor enhancer.
-
Prostaglandin E1-d4
0 ImagesCat. No.: HY-B0131SCAS No.: 211105-33-8Prostaglandin E1-d4 is the deuterium labeled Prostaglandin E1. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases.
-
Terbinafine-d3
0 ImagesCat. No.: HY-17395AS1CAS No.: 1133210-36-2Synonyms: TDT 067-d3Terbinafine-d3 (TDT 067-d3) is deuterium labeled Terbinafine. Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
-
Allyl methyl disulfide-d3
0 ImagesCat. No.: HY-W142921SCAS No.: 3028869-67-9Synonyms: Methyl prop-2-en-1-yl disulfide-d3Allyl methyl disulfide-d3 is deuterated labeled Allyl methyl disulfide.
-
β-Thujene-d2
0 ImagesCat. No.: HY-156485Sβ-Thujene-d2 is deuterated labeled β-Thujene.
-
3,4-Dihydro-6-methoxy-7-isoquinolinol-d3
0 ImagesCat. No.: HY-W097910S3,4-Dihydro-6-methoxy-7-isoquinolinol-d3 is the deuterium labeled 3,4-Dihydro-6-methoxy-7-isoquinolinol.
-
Sodium octyl sulfate (SOS)-d17
0 ImagesCat. No.: HY-W096997SCAS No.: 1219802-16-0Synonyms: Sodium capryl sulfate-d17Sodium octyl sulfate (SOS)-d17 (Sodium capryl sulfate-d17) is the deuterated analogue of Sodium octyl sulfate (SOS). Sodium octyl sulfate (Sodium capryl sulfate; SOS) is a medium‑chain anionic surfactant. Sodium octyl sulfate (SOS) can undergo strong hydrophobic interactions with serum albumins (such as human serum albumin (HSA) and bovine serum albumin (BSA)), while exhibiting weak interactions with other proteins including myoglobin and hemoglobin. As an environmental pollutant in freshwater ecosystems, Sodium octyl sulfate (SOS) can mimic interspecific pheromones released by Daphnia magna and induce the formation of multicellular colonies in green algae.
-
Chlordene-13C10
0 ImagesCat. No.: HY-166956SChlordene-13C10 is 13C labeled 1,7,8,9,10,10-Hexachlorotricyclo[5.2.1.0,2,6]deca-3,8-diene.
-
Selegiline-d5
0 ImagesCat. No.: HY-14198SCAS No.: 1217976-51-6Synonyms: Deprenyl-d5; (-)-Selegiline-d5; (-)-Deprenyl-d5Selegiline-d5 (Deprenyl-d5) is deuterium labeled Selegiline. Selegiline (Deprenyl) is a potent, selective and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. Selegiline exhibits 450-flod selectivity for MAO-B over MAO-A (IC50=23 μM). Selegiline can be used for the research of Parkinson's disease, Alzheimer's disease and major depressive disorder.
-
D-Erythro-sphingosine-1-phosphate-13C2,d2
0 ImagesCat. No.: HY-W654343CAS No.: 2734928-88-0D-Erythro-sphingosine-1-phosphate-13C2,d2 is 13C labeled D-Erythro-sphingosine-1-phosphate.
-
N-(2,6-Dimethylphenyl)-N-(2-sulfoacetyl)glycine-d9
0 ImagesCat. No.: HY-W725080SN-(2,6-Dimethylphenyl)-N-(2-sulfoacetyl)glycine-d9 is deuterium labeled N-(2,6-Dimethylphenyl)-N-(2-sulfoacetyl)glycine.
