Oxysterol-binding Protein-related Protein (ORP) Degrader
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PROTAC OSBP Degrader-1
0 ImagesCat. No.: HY-178034PROTAC OSBP Degrader-1 is a CRBN-dependent oxysterol-binding protein (OSBP) PROTAC degrader with a DC50 of 322 nM. PROTAC OSBP Degrader-1 exhibits high specificity for OSBP over other ORP family proteins. PROTAC OSBP Degrader-1 directly interacts with OSBP, possesses rapid cell-penetrating ability, and shows cytotoxicity against cancer cells. PROTAC OSBP Degrader-1 can be used in the research of glioblastoma, lung cancer, triple-negative breast cancer and cervical cancer.
