Phosphoglycerate Dehydrogenase (PHGDH) Degrader
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LXH-3-71
0 ImagesCat. No.: HY-177742CAS No.: 2251753-65-6LXH-3-71 is a PHGDH degrader. LXH-3-71 acts as a molecular glue to enhance the interaction of the PHGDH-DDB1-CRL E3 ligase complex, triggering ubiquitination and proteasomal degradation of PHGDH. LXH-3-71 regulates the stemness of colorectal cancer cells and inhibits tumor proliferation and colony formation. LXH-3-71 can be used in the research of colorectal cancer.
