1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
  3. Piezo Channel
  4. Piezo Channel Antagonist

Piezo Channel Antagonist

Piezo Channel Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-126010
    Dooku1
    Antagonist 99.89%
    Dooku1 is a reversibly Yoda1 antagonist with IC50 value of 1.3 μM and 1.5 μM for 2 μM Yoda1-induced Ca2+ entry HEK 293 cells and HUVECs, respectively. Dooku1 can disrupt Yoda1-induced Piezo1 channel activity and inhibit Yoda1-induced relaxation of aorta. Dooku1 can be used for vascular physiology and disease research.