1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. Amthamine dihydrobromide

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .

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Amthamine dihydrobromide

Amthamine dihydrobromide Estructura química

No. CAS : 142457-00-9

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
100 mg   Obtener un presupuesto  
200 mg   Obtener un presupuesto  

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Descripciòn

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1].

Peso molecular

319.07

Fòrmula

C6H13Br2N3S

No. CAS
Appearance

Solid

Color

White to yellow

SMILES

NCCC1=C(C)N=C(N)S1.Br.Br

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

H2O : 100 mg/mL (313.41 mM; Need ultrasonic)

DMSO : 83.33 mg/mL (261.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1341 mL 15.6707 mL 31.3415 mL
5 mM 0.6268 mL 3.1341 mL 6.2683 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: 99.64%

Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.1341 mL 15.6707 mL 31.3415 mL 78.3537 mL
5 mM 0.6268 mL 3.1341 mL 6.2683 mL 15.6707 mL
10 mM 0.3134 mL 1.5671 mL 3.1341 mL 7.8354 mL
15 mM 0.2089 mL 1.0447 mL 2.0894 mL 5.2236 mL
20 mM 0.1567 mL 0.7835 mL 1.5671 mL 3.9177 mL
25 mM 0.1254 mL 0.6268 mL 1.2537 mL 3.1341 mL
30 mM 0.1045 mL 0.5224 mL 1.0447 mL 2.6118 mL
40 mM 0.0784 mL 0.3918 mL 0.7835 mL 1.9588 mL
50 mM 0.0627 mL 0.3134 mL 0.6268 mL 1.5671 mL
60 mM 0.0522 mL 0.2612 mL 0.5224 mL 1.3059 mL
80 mM 0.0392 mL 0.1959 mL 0.3918 mL 0.9794 mL
100 mM 0.0313 mL 0.1567 mL 0.3134 mL 0.7835 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Amthamine dihydrobromide
Cat. No.:
HY-101063
Cantidad:
MCE Japan Authorized Agent: