ADCYAP1 Antibody (YA7234)
(Synonyms: Pituitary adenylate cyclase-activating polypeptide, PACAP, ADCYAP1)ADCYAP1 Antibody (YA7234) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ADCYAP1.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
WB
-
Reactivity :
Human
-
Formulation:
Supplied in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000-4000 |
Product Details
ADCYAP1 Antibody (YA7234) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ADCYAP1.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Calculated Molecular Weight Predicted band size: 19 kDa;
Recombinant human ADCYAP1
Endogenous
affinity purified by Protein G
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
ADCYAP1 is a PACAP is a neuropeptide involved in diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR2), and PACAP type I receptor (ADCYAP1R1). Exerts neuroprotective and general cytoprotective effects due to anti-apoptotic, anti-inflammatory, and antioxidant actions. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. PACAP exists in two bioactive forms from proteolysis of the same precursor protein, PACAP27 and PACAP38, which differ by eleven amino acid residues in the C-terminus[1][2][3][4].
-
Subcellular Localization
Secreted
-
Isoforms & Post-Translational Modification
P18509: 176 amino acids, molecular weight 18835 Da.
-
SwissProt ID
-
Synonyms
Pituitary adenylate cyclase-activating polypeptide, PACAP, ADCYAP1
Documentation
Powered by Bioz
