Caveolin 3 Antibody (YA2869)
(Synonyms: CAV3; M-caveolin; Caveolin 3; VIP21)Caveolin 3 Antibody (YA2869) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caveolin 3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50 |
Product Details
Caveolin 3 Antibody (YA2869) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caveolin 3.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 17 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 17 kDa
Entrez Gene: 859 Human ; 12391 Mouse ; 29161 Rat
SwissProt: P56539 Human ; P51637 Mouse ; P51638 Rat
OMIM: 123320 Human
A synthesized peptide derived from human Caveolin-3 aa1-60.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Caveolin 3 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae[1].
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Subcellular Localization
Golgi apparatus membrane; Peripheral membrane protein; Cell membrane; Peripheral membrane protein; Membrane, caveola; Peripheral membrane protein; Cell membrane, sarcolemma
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Expression
Tissue_specificity:Expressed predominantly in muscle -
Subunit
Homooligomer. Interacts with DLG1 and KCNA5; forms a ternary complex. Interacts with TRIM72. Interacts with MUSK; may regulate MUSK signaling.
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SwissProt ID
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Synonyms
CAV3; M-caveolin; Caveolin 3; VIP21
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Research Field
Signal Transduction
Documentation
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