CD39 Antibody (YA1094)(PBS only)

(Synonyms: CD39; ENTPD1; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1; Ecto-ATPase 1); Ecto-apyrase; Lymphoid cell activation antigen)

CD39 Antibody (YA1094) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD39.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:100-1:200

Product Details

Description

CD39 Antibody (YA1094) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD39.

  • Host Rabbit
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 70 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 58 kDa
Immunogen

Recombinant protein of human CD39

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CD39 catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow[1][2][3][4].

  • Subcellular Localization

    Membrane; Multi-pass membrane protein; Membrane, caveola

  • Expression


    Tissue_specificity:It is primarily expressed on activated lymphocytes (PubMed:7930580) . It is also expressed in endothelial tissues (PubMed:8955160) . It is highly expressed in the placenta, lungs, skeletal muscle, and kidneys (PubMed:8955160) .

  • Isoforms & Post-Translational Modification

    P49961 has 6 isomers: P49961-1: 57965 Da (predicted); P49961-2: 58706 Da (predicted); P49961-3: 34175 Da (predicted); P49961-4: 42731 Da (predicted); P49961-5: 46180 Da (predicted); P49961-6: 59325 Da (predicted).
    N-glycosylated;The N-terminus is blocked;Palmitoylated on Cys-13; which is required for caveola targeting

  • Subunit

    Homodimer; disulfide-linked

  • SwissProt ID

    P49961

  • Gene ID
    953 [NCBI]
  • Synonyms

    CD39; ENTPD1; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1; Ecto-ATPase 1); Ecto-apyrase; Lymphoid cell activation antigen

  • Research Field

    Immunology

CD39 Antibody (YA1094)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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