CD39 Antibody (YA1094)(PBS only)
(Synonyms: CD39; ENTPD1; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1; Ecto-ATPase 1); Ecto-apyrase; Lymphoid cell activation antigen)CD39 Antibody (YA1094) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD39.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
CD39 Antibody (YA1094) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD39.
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Host Rabbit
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 70 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 58 kDa
Recombinant protein of human CD39
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD39 catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow[1][2][3][4].
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Subcellular Localization
Membrane; Multi-pass membrane protein; Membrane, caveola
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Expression
Tissue_specificity:It is primarily expressed on activated lymphocytes (PubMed:7930580) . It is also expressed in endothelial tissues (PubMed:8955160) . It is highly expressed in the placenta, lungs, skeletal muscle, and kidneys (PubMed:8955160) . -
Isoforms & Post-Translational Modification
P49961 has 6 isomers: P49961-1: 57965 Da (predicted); P49961-2: 58706 Da (predicted); P49961-3: 34175 Da (predicted); P49961-4: 42731 Da (predicted); P49961-5: 46180 Da (predicted); P49961-6: 59325 Da (predicted).
N-glycosylated;The N-terminus is blocked;Palmitoylated on Cys-13; which is required for caveola targeting -
Subunit
Homodimer; disulfide-linked
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SwissProt ID
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Synonyms
CD39; ENTPD1; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1; Ecto-ATPase 1); Ecto-apyrase; Lymphoid cell activation antigen
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Research Field
Immunology
Documentation