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Cat. No.: HY-P87653

CD39L4 Antibody (YA7337)

CD39L4 Antibody (YA7337) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD39L4.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	IHC-F IHC-F: Immunohistochemistry-Frozen	IF-Tissue IF-Tissue: Immunofluorescence-Tissue	IP IP: Immunoprecipitation
Dilution Ratio	1:1000-2000	1:100-200	1:100-200	1:100-200	1:20-50

Description

CD39L4 Antibody (YA7337) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD39L4.

Host Rabbit
Clonality Recombinant,Monoclonal
Species Reactivity
Mouse, Rat Predicted Reactivity: Human

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
Observed Molecular Weight

Observed band size: 47 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 48 kDa

Immunogen

A synthesized peptide derived from human ENTPD5

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

CD39L4 hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP. In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER^[1]^[2].
Subcellular Localization

Endoplasmic reticulum,Secreted
Expression

Tissue_Specificity: Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues
Induction: Up-regulated in cell lines and primary tumor samples with active AKT1
Isoforms & Post-Translational Modification

O75356: 428 amino acids, molecular weight 47517 Da.
Subunit

Monomer; active form (PubMed:12508121)
SwissProt ID

O75356