CDC42SE2 Antibody (YA8733)

Cat. No.: HY-P89049: Data Sheet User Guide for Antibodies
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CDC42SE2 Antibody (YA8733) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDC42SE2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CDC42SE2 Antibody (YA8733) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDC42SE2.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 9 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9NRR3

Immunogen

Full length human recombinant protein of human CDC42SE2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages

Subcellular Localization：Cytoplasm, cytoskeleton,Cell membrane,Cell projection, phagocytic cup

Expression：
Tissue_Specificity: Widely expressed. Expressed at higher level in T-lymphocytes. Highly expressed in CCRF-CEM T-lymphocytes, Jurkat T-lymphocytes, and Raji B-lymphocytes compared (at protein level)

Isoforms & Post-Translational Modification：Q9NRR3: 84 amino acids, molecular weight 9223 Da.

Subunit：Interacts with CDC42 (in GTP-bound form)

Synonyms

SPEC2

Documentation

User Guide for Antibodies (1077 KB)