CDC42SE2 Antibody (YA8733)
(Synonyms: SPEC2)CDC42SE2 Antibody (YA8733) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDC42SE2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
CDC42SE2 Antibody (YA8733) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDC42SE2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 9 kDa
Full length human recombinant protein of human CDC42SE2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CDC42SE2 is a Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages
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Subcellular Localization
Cytoplasm, cytoskeleton,Cell membrane,Cell projection, phagocytic cup
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Expression
Tissue_Specificity: Widely expressed. Expressed at higher level in T-lymphocytes. Highly expressed in CCRF-CEM T-lymphocytes, Jurkat T-lymphocytes, and Raji B-lymphocytes compared (at protein level) -
Isoforms & Post-Translational Modification
Q9NRR3: 84 amino acids, molecular weight 9223 Da.
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Subunit
Interacts with CDC42 (in GTP-bound form)
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SwissProt ID
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Synonyms
SPEC2
Documentation
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