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CECR5 Antibody (YA2477)

(Synonyms: haloacid dehalogenase like hydrolase domain containing 5; CECR5)

CECR5 Antibody (YA2477) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CECR5.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IP

  • Reactivity :

    Human

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Conjugation:
    Non-conjugated
  • CECR5 Antibody (YA2477) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:500-1:1000 1:20

Product Details

Description

CECR5 Antibody (YA2477) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CECR5.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 46 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 46 kDa
Species Reactivity Database

Entrez Gene: 27440 Human

SwissProt: Q9BXW7 Human

Immunogen

A synthetic peptide of human CECR5

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    The mitochondrial-related gene Haloacid dehalogenase-like hydrolase domain-containing 5 (HDHD5, also known as CECR5) as being markedly upregulated in triple-negative breast cancer tissues relative to matched adjacent normal tissues. HDHD5 has been reported to localize to mitochondria and to be closely involved in the regulation of mitochondrial function and lipid metabolism. HDHD5 is highly expressed in colorectal cancer[1].

  • Subcellular Localization

    mitochondrion

  • Isoforms & Post-Translational Modification

    CECR5 has 2 isomers: Q9BXW7-1: 46321 Da (predicted); Q9BXW7-2: 43588 Da (predicted).

  • SwissProt ID

    Q9BXW7

  • Gene ID
    27440 [NCBI]
  • Synonyms

    haloacid dehalogenase like hydrolase domain containing 5; CECR5

  • Research Field

    Cell Biology

References

[1]. Cai JY, et al. HDHD5 promotes triple-negative breast cancer growth and drives EMT-associated phenotypes via regulating S100A4. J Cancer Res Clin Oncol. 2026 Apr 29;152(4):101.

CECR5 Antibody (YA2477) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CECR5 Antibody (YA2477) Product Image