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Cat. No.: HY-P88590

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EARS2 Antibody (YA8274)

Name: EARS2 Antibody (YA8274)
Brand: MedChemExpress
SKU: HY-P88590
Availability: PreOrder

(Synonyms: COXPD12; gluRS; MSE1)

EARS2 Antibody (YA8274) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EARS2.

For research use only. We do not sell to patients.

Host:
Mouse
Isotype:
IgG1
Application:
IHC-P
Reactivity :
Human, Mouse, Rat

Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Conjugation:
Non-conjugated

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications
Product Details
Product Properties
- Appearance
- Formulation
- Storage & Stability
- Shipping
Background
Documentation
Help & FAQs
Classifications
Bioz

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio	1:500-800

Product Details

Description

EARS2 Antibody (YA8274) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EARS2.

Host Mouse
Clonality Monoclonal
Species Reactivity
Human, Mouse, Rat
Calculated Molecular Weight Predicted band size: 58.5 kDa

Immunogen

Full length human recombiant protein of human EARS2 produced in E.coli.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

Appearance

Liquid
Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Background

Function

EARS2 is a Non-discriminating glutamyl-tRNA synthetase that catalyzes aminoacylation of both mitochondrial tRNA(Glu) and tRNA(Gln) and participates in RNA aminoacylation for mitochondrial protein translation. Attachs glutamate to tRNA(Glu) or tRNA(Gln) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) or tRNA(Gln). In vitro, cytoplasmic tRNA(Gln) is slightly glutamylated, but with low activity^[1].
Subcellular Localization

Mitochondrion matrix
Isoforms & Post-Translational Modification

Q5JPH6 has two isomers: Q5JPH6-1: 58689 Da (predicted); Q5JPH6-2: 59989 Da (predicted).
SwissProt ID

Q5JPH6
Synonyms

COXPD12; gluRS; MSE1