EARS2 Antibody (YA8274)

Cat. No.: HY-P88590: Data Sheet User Guide for Antibodies
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EARS2 Antibody (YA8274) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EARS2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

EARS2 Antibody (YA8274) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EARS2.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 58.5 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q5JPH6

Immunogen

Full length human recombiant protein of human EARS2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Non-discriminating glutamyl-tRNA synthetase that catalyzes aminoacylation of both mitochondrial tRNA(Glu) and tRNA(Gln) and participates in RNA aminoacylation for mitochondrial protein translation (PubMed:19805282). Attachs glutamate to tRNA(Glu) or tRNA(Gln) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) or tRNA(Gln) (PubMed:19805282). In vitro, cytoplasmic tRNA(Gln) is slightly glutamylated, but with low activity (PubMed:19805282)

Subcellular Localization：Mitochondrion matrix

Isoforms & Post-Translational Modification：Q5JPH6 has two isomers: Q5JPH6-1: 58689 Da (predicted); Q5JPH6-2: 59989 Da (predicted).

Synonyms

COXPD12; gluRS; MSE1

Documentation

User Guide for Antibodies (1077 KB)