FGFBP1 Antibody (YA7940)
(Synonyms: FGF-BP; FGF-BP1; FGFBP; FGFBP-1; HBP17)
Based on 1 Customer Validation
FGFBP1 Antibody (YA7940) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGFBP1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:2000 | 1:150-500 |
Product Details
FGFBP1 Antibody (YA7940) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGFBP1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 26.1 kDa
Human recombinant protein fragment corresponding to amino acids 24-234 of human FGFBP1 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
FGFBP1 acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth
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Subcellular Localization
Secreted, extracellular space,Cell membrane
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Expression
Tissue_Specificity: Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas
Induction: Up-regulated in epithelial cells after skin injury. Keratinocyte mitogens -
Isoforms & Post-Translational Modification
Q14512: 234 amino acids, molecular weight 26264 Da.
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Subunit
Found in a complex with FGFBP1, FGF1 and FGF2
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SwissProt ID
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Synonyms
FGF-BP; FGF-BP1; FGFBP; FGFBP-1; HBP17
Documentation
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